ADAR1 isoform involvement in embryonic lethality.
作者信息
Steinman Richard A, Wang Qingde
出版信息
Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):E199; author reply E200. doi: 10.1073/pnas.1105004108. Epub 2011 May 18.
Abstract
摘要
相似文献
1
ADAR1 isoform involvement in embryonic lethality.
Proc Natl Acad Sci U S A. 2011 Jun 14;108(24):E199; author reply E200. doi: 10.1073/pnas.1105004108. Epub 2011 May 18.
2
Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?
Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):E43; author reply E44. doi: 10.1073/pnas.1100419108. Epub 2011 Mar 14.
3
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.
Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6. doi: 10.1073/pnas.1017241108. Epub 2010 Dec 20.
4
Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing.
J Biol Chem. 2005 Apr 15;280(15):15020-8. doi: 10.1074/jbc.M500476200. Epub 2005 Jan 25.
5
The RNA-editing enzyme ADAR1 controls innate immune responses to RNA.
Cell Rep. 2014 Nov 20;9(4):1482-94. doi: 10.1016/j.celrep.2014.10.041. Epub 2014 Nov 13.
6
Altered A-to-I RNA editing in human embryogenesis.
PLoS One. 2012;7(7):e41576. doi: 10.1371/journal.pone.0041576. Epub 2012 Jul 31.
7
Identification and characterization of a constitutively expressed Ctenopharyngodon idella ADAR1 splicing isoform (CiADAR1a).
Dev Comp Immunol. 2016 Oct;63:10-7. doi: 10.1016/j.dci.2016.05.008. Epub 2016 May 13.
8
ADAR1 RNA deaminase limits short interfering RNA efficacy in mammalian cells.
J Biol Chem. 2005 Feb 4;280(5):3946-53. doi: 10.1074/jbc.M407876200. Epub 2004 Nov 19.
9
The RNA-Specific Adenosine Deaminase ADAR1 Inhibits Human Protein Kinase R Activation.
Viral Immunol. 2018 Sep;31(7):537-538. doi: 10.1089/vim.2018.0056. Epub 2018 Jun 8.
10
A splicing isoform of Ctenopharyngodon idella ADAR1 (CiADAR1-like): Genome organization, tissue specific expression and transcriptional regulation.
Fish Shellfish Immunol. 2015 Nov;47(1):535-44. doi: 10.1016/j.fsi.2015.09.040. Epub 2015 Oct 9.
引用本文的文献
1
ADARs: pleiotropy in function, versatility in application.
Nucleic Acids Res. 2025 Jul 8;53(13). doi: 10.1093/nar/gkaf672.
2
ADAR1 Zα domain P195A mutation activates the MDA5-dependent RNA-sensing signaling pathway in brain without decreasing overall RNA editing.
Cell Rep. 2023 Jul 25;42(7):112733. doi: 10.1016/j.celrep.2023.112733. Epub 2023 Jul 6.
3
Generation of a new mouse demonstrates isoform-specific roles in embryonic development and adult homeostasis.
RNA. 2023 Sep;29(9):1325-1338. doi: 10.1261/rna.079509.122. Epub 2023 Jun 8.
4
The phenotype of the most common human ADAR1p150 Zα mutation P193A in mice is partially penetrant.
EMBO Rep. 2023 May 4;24(5):e55835. doi: 10.15252/embr.202255835. Epub 2023 Mar 28.
5
ADAR1 RNA editing regulates endothelial cell functions via the MDA-5 RNA sensing signaling pathway.
Life Sci Alliance. 2021 Dec 30;5(3). doi: 10.26508/lsa.202101191. Print 2022 Mar.
6
RNA editing at a limited number of sites is sufficient to prevent MDA5 activation in the mouse brain.
PLoS Genet. 2021 May 13;17(5):e1009516. doi: 10.1371/journal.pgen.1009516. eCollection 2021 May.
7
The Role of RNA Editing in Cancer Development and Metabolic Disorders.
Front Endocrinol (Lausanne). 2018 Dec 18;9:762. doi: 10.3389/fendo.2018.00762. eCollection 2018.
8
ADAR1-Mediated RNA Editing, A Novel Mechanism Controlling Phenotypic Modulation of Vascular Smooth Muscle Cells.
Circ Res. 2016 Jul 22;119(3):463-9. doi: 10.1161/CIRCRESAHA.116.309003. Epub 2016 May 19.
9
PTBP1 induces ADAR1 p110 isoform expression through IRES-like dependent translation control and influences cell proliferation in gliomas.
Cell Mol Life Sci. 2015 Nov;72(22):4383-97. doi: 10.1007/s00018-015-1938-7. Epub 2015 Jun 6.
10
Mouse models for Aicardi-Goutières syndrome provide clues to the molecular pathogenesis of systemic autoimmunity.
Clin Exp Immunol. 2014 Jan;175(1):9-16. doi: 10.1111/cei.12147.
本文引用的文献
1
Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?
Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):E43; author reply E44. doi: 10.1073/pnas.1100419108. Epub 2011 Mar 14.
2
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.
Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6. doi: 10.1073/pnas.1017241108. Epub 2010 Dec 20.
3
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene.
J Biol Chem. 2004 Feb 6;279(6):4952-61. doi: 10.1074/jbc.M310162200. Epub 2003 Nov 12.
Zotero 插件