Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?
作者信息
Matthaei Klaus I, Frese Michael, Hill Caryl E
出版信息
Proc Natl Acad Sci U S A. 2011 Mar 22;108(12):E43; author reply E44. doi: 10.1073/pnas.1100419108. Epub 2011 Mar 14.
Abstract
摘要
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Is the p150 isoform of the RNA editing enzyme Adenosine Deaminase 1 really responsible for embryonic lethality?RNA编辑酶腺苷脱氨酶1的p150同工型真的是胚胎致死的原因吗？
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ADAR1 isoform involvement in embryonic lethality.ADAR1亚型与胚胎致死性的关系。
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本文引用的文献
1
RNA editing enzyme adenosine deaminase is a restriction factor for controlling measles virus replication that also is required for embryogenesis.RNA 编辑酶腺苷脱氨酶是一种限制因子，可控制麻疹病毒的复制，对于胚胎发生也是必需的。
Proc Natl Acad Sci U S A. 2011 Jan 4;108(1):331-6. doi: 10.1073/pnas.1017241108. Epub 2010 Dec 20.
2
ADAR1 is essential for the maintenance of hematopoiesis and suppression of interferon signaling.ADAR1对于维持造血功能和抑制干扰素信号传导至关重要。
Nat Immunol. 2009 Jan;10(1):109-15. doi: 10.1038/ni.1680. Epub 2008 Dec 7.
3
Role of nucleophosmin in embryonic development and tumorigenesis.核磷蛋白在胚胎发育和肿瘤发生中的作用。
Nature. 2005 Sep 1;437(7055):147-53. doi: 10.1038/nature03915. Epub 2005 Jul 6.
4
Expression of interferon-inducible RNA adenosine deaminase ADAR1 during pathogen infection and mouse embryo development involves tissue-selective promoter utilization and alternative splicing.干扰素诱导的RNA腺苷脱氨酶ADAR1在病原体感染和小鼠胚胎发育过程中的表达涉及组织选择性启动子的利用和可变剪接。
J Biol Chem. 2005 Apr 15;280(15):15020-8. doi: 10.1074/jbc.M500476200. Epub 2005 Jan 25.
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