Department of Radiology, Beijing Hospital, No. 1 Dahua Road, Dongcheng, Beijing, China.
J Altern Complement Med. 2011 May;17(5):413-20. doi: 10.1089/acm.2010.0322.
The aim of this study was to use magnetic resonance imaging (MRI) together with proton magnetic resonance spectroscopy ((1)H-MRS) to study the influence of acupuncture therapy on abdominal fat and hepatic fat content in obese children.
The design was a longitudinal, clinical intervention study of acupuncture therapy.
SUBJECTS were 10 healthy, obese children (age: 11.4 ± 1.65 years, body-mass index [BMI]: 29.03 ± 4.81 kg/m(2)).
Measurements included various anthropometric parameters, abdominal fat (assessed by MRI) and hepatic fat content (assessed by (1)H-MRS) at baseline and after 1 month of acupuncture therapy.
One (1) month of acupuncture therapy significantly reduced the subjects' BMI by 3.5% (p = 0.005), abdominal visceral adipose tissue (VAT) volume by 16.04% (p < 0.0001), abdominal total adipose tissue volume by 10.45% (p = 0.001), and abdominal visceral to subcutaneous fat ratio by 10.59% (p = 0.007). Decreases in body weight (-2.13%), waist circumference (-1.44%), hip circumference (-0.33%), waist-to-hip ratio (WHR) (-0.99%), abdominal subcutaneous adipose tissue (SAT) volume (-5.63%), and intrahepatic triglyceride (IHTG) content (-9.03%) were also observed, although these were not significant (p > 0.05). There was a significant correlation between the level of abdominal fat (SAT, VAT) and anthropometric parameters (weight, BMI, waist circumferences, hip circumferences). There was no statistically significant correlation between IHTG and anthropometric parameters or abdominal fat content.
The first direct experimental evidence is provided demonstrating that acupuncture therapy significantly reduces BMI and abdominal adipose tissue by reducing abdominal VAT content without significant changes in body weight, waist circumference, hip circumference, WHR, abdominal SAT, or IHTG content. Thus, the use of acupuncture therapy to selectively target a reduction in abdominal VAT content should become more important and more popular in the future.
本研究旨在使用磁共振成像（MRI）和质子磁共振波谱（1H-MRS）研究针刺疗法对肥胖儿童腹部脂肪和肝内脂肪含量的影响。
这是一项关于针刺疗法的纵向临床干预研究。
10 名健康肥胖儿童（年龄：11.4±1.65 岁，体重指数[BMI]：29.03±4.81kg/m2）。
包括各种人体测量参数、腹部脂肪（MRI 评估）和肝内脂肪含量（1H-MRS 评估），在基线和针刺治疗 1 个月后进行测量。
针刺治疗 1 个月后，受试者 BMI 降低了 3.5%（p=0.005），腹部内脏脂肪组织（VAT）体积降低了 16.04%（p<0.0001），腹部总脂肪组织体积降低了 10.45%（p=0.001），腹部内脏脂肪与皮下脂肪比值降低了 10.59%（p=0.007）。体重（-2.13%）、腰围（-1.44%）、臀围（-0.33%）、腰臀比（WHR）（-0.99%）、腹部皮下脂肪（SAT）体积（-5.63%）和肝内甘油三酯（IHTG）含量（-9.03%）也有下降，但无统计学意义（p>0.05）。腹部脂肪（SAT、VAT）与人体测量参数（体重、BMI、腰围、臀围）之间存在显著相关性。IHTG 与人体测量参数或腹部脂肪含量之间无统计学相关性。
本研究首次提供了直接的实验证据，表明针刺疗法可通过降低腹部 VAT 含量来显著降低 BMI 和腹部脂肪组织，而体重、腰围、臀围、WHR、腹部 SAT 或 IHTG 含量无显著变化。因此，未来针刺疗法选择性靶向减少腹部 VAT 含量将变得更加重要和流行。
