采用气液色谱法和苯萃取法测定血浆中劳拉西泮的含量。

Estimation of plasma lorazepam by gas-liquid chromatography and a benzene extraction.

作者信息

Howard P J, Lilburn J K, Dundee J W, Toner W, McIlroy P D

出版信息

Anaesthesia. 1977 Sep;32(8):767-70. doi: 10.1111/j.1365-2044.1977.tb10078.x.

DOI:10.1111/j.1365-2044.1977.tb10078.x

Abstract

Plasma lorazepam can be easily and reliably estimated using a simple single stage benzene extraction and gas-lizuid chromatography with flunitrazepam as the internal standard. Reproducible results within the clinical range of plasma levels were obtained. This method permits the extraction and chromatographing of 40 samples in approximately 7 1/2 hours.

摘要

血浆中劳拉西泮可以通过简单的单步苯萃取和以氟硝西泮为内标的气相-液相色谱法轻松且可靠地测定。在血浆水平的临床范围内获得了可重复的结果。该方法允许在约7个半小时内萃取和色谱分析40个样品。