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Eur Ann Otorhinolaryngol Head Neck Dis. 2011 Sep;128(4):197-9. doi: 10.1016/j.anorl.2011.01.005. Epub 2011 May 18.
Mycobacterium fortuitum, a rapidly growing non-tuberculous atypical mycobacterium, is commonly found in soil and water. This organism generally causes skin, bone, and soft tissue infections following local trauma or surgical procedures, and in immunodeficient patients. The case reported here is, to our knowledge, the first published report of M. fortuitum nasal infection.
The authors report the case of a 3-year-old girl with intranasal tumour-like swelling associated with cervical lymph nodes due to M. fortuitum infection.
DISCUSSION/CONCLUSION: A combination of radical surgical debridement and prolonged therapy with several antimicrobial agents was required to completely eradicate the infection. This case report indicates that non-tuberculous mycobacterial infections should be considered after failure of conventional antibiotic therapy or when classical microbiological tests fail to identify the pathogen responsible for sinonasal and cervical infections.
偶然分枝杆菌是一种生长迅速的非结核非典型分枝杆菌,常见于土壤和水中。该病原体通常在局部创伤或外科手术后以及免疫功能低下的患者中引起皮肤、骨骼和软组织感染。据我们所知,本报告所报道的病例是首例偶然分枝杆菌鼻感染病例。
作者报告了一例 3 岁女孩因感染偶然分枝杆菌而出现鼻腔内肿瘤样肿胀并伴有颈部淋巴结肿大。
讨论/结论:需要彻底清除感染,需要结合彻底的外科清创术和多种抗菌药物的长期治疗。本病例报告表明,在常规抗生素治疗失败或经典微生物学检测未能确定导致鼻和颈部感染的病原体时,应考虑非结核分枝杆菌感染。