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阿曼急性冠状动脉综合征患者代谢综合征的患病率、特征和院内结局。

Prevalence, characteristics, and in-hospital outcomes of metabolic syndrome among acute coronary syndrome patients from Oman.

机构信息

Department of Clinical Biochemistry, Sultan Qaboos University Hospital, Muscat, Oman.

出版信息

Angiology. 2011 Jul;62(5):381-9. doi: 10.1177/0003319710382419.

Abstract

We evaluated in-hospital outcomes of acute coronary syndrome (ACS) patients with metabolic syndrome (MetS) in Oman. We analyzed the records of 1392 patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events. The prevalence of MetS among patients with ACS was 66%, with female preponderance (80% vs 57%; P < .001). MetS was associated with several characteristics including diabetes (45% vs 19%; P < .001), hyperlipidemia (40% vs 23%; P < .001), hypertension (62% vs 34%; P < .001), renal impairment (9.3% vs 3.4%; P < .001), Killip score > II (13% vs 8%; P = .004), and non-ST segment elevation myocardial infarction (78% vs 68%; P < .001). After multivariate adjustment, MetS was associated with higher risk of in-hospital heart failure (odds ratio [OR], 1.37; 95% CI: 1.03-1.81; P = .028) and mortality (OR, 4.42; 95% CI: 1.25-15.5; P = .020). Prevalence of MetS among patients with ACS in Oman is high. MetS was associated with higher in-hospital heart failure and mortality.

摘要

我们评估了阿曼急性冠状动脉综合征(ACS)患者合并代谢综合征(MetS)的住院结局。我们分析了作为海湾急性冠状动脉事件登记研究一部分而收治的 1392 例 ACS 患者的记录。ACS 患者中 MetS 的患病率为 66%,女性居多(80%比 57%;P <.001)。MetS 与多种特征相关,包括糖尿病(45%比 19%;P <.001)、血脂异常(40%比 23%;P <.001)、高血压(62%比 34%;P <.001)、肾功能不全(9.3%比 3.4%;P <.001)、Killip 分级> II 级(13%比 8%;P =.004)和非 ST 段抬高型心肌梗死(78%比 68%;P <.001)。经多变量调整后,MetS 与住院期间心力衰竭(比值比 [OR],1.37;95%置信区间:1.03-1.81;P =.028)和死亡率(OR,4.42;95%置信区间:1.25-15.5;P =.020)风险增加相关。阿曼 ACS 患者中 MetS 的患病率较高。MetS 与住院期间心力衰竭和死亡率增加相关。

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