Department of Clinical Biochemistry, Sultan Qaboos University Hospital, Muscat, Oman.
Angiology. 2011 Jul;62(5):381-9. doi: 10.1177/0003319710382419.
We evaluated in-hospital outcomes of acute coronary syndrome (ACS) patients with metabolic syndrome (MetS) in Oman. We analyzed the records of 1392 patients admitted with a diagnosis of ACS as part of the Gulf Registry of Acute Coronary Events. The prevalence of MetS among patients with ACS was 66%, with female preponderance (80% vs 57%; P < .001). MetS was associated with several characteristics including diabetes (45% vs 19%; P < .001), hyperlipidemia (40% vs 23%; P < .001), hypertension (62% vs 34%; P < .001), renal impairment (9.3% vs 3.4%; P < .001), Killip score > II (13% vs 8%; P = .004), and non-ST segment elevation myocardial infarction (78% vs 68%; P < .001). After multivariate adjustment, MetS was associated with higher risk of in-hospital heart failure (odds ratio [OR], 1.37; 95% CI: 1.03-1.81; P = .028) and mortality (OR, 4.42; 95% CI: 1.25-15.5; P = .020). Prevalence of MetS among patients with ACS in Oman is high. MetS was associated with higher in-hospital heart failure and mortality.
我们评估了阿曼急性冠状动脉综合征（ACS）患者合并代谢综合征（MetS）的住院结局。我们分析了作为海湾急性冠状动脉事件登记研究一部分而收治的 1392 例 ACS 患者的记录。ACS 患者中 MetS 的患病率为 66%，女性居多（80%比 57%；P <.001）。MetS 与多种特征相关，包括糖尿病（45%比 19%；P <.001）、血脂异常（40%比 23%；P <.001）、高血压（62%比 34%；P <.001）、肾功能不全（9.3%比 3.4%；P <.001）、Killip 分级> II 级（13%比 8%；P =.004）和非 ST 段抬高型心肌梗死（78%比 68%；P <.001）。经多变量调整后，MetS 与住院期间心力衰竭（比值比 [OR]，1.37；95%置信区间：1.03-1.81；P =.028）和死亡率（OR，4.42；95%置信区间：1.25-15.5；P =.020）风险增加相关。阿曼 ACS 患者中 MetS 的患病率较高。MetS 与住院期间心力衰竭和死亡率增加相关。
