Division of Clinical Epidemiology and Aging Research, German Cancer Research Center, Heidelberg, Germany.
Ann Oncol. 2012 Feb;23(2):472-9. doi: 10.1093/annonc/mdr131. Epub 2011 May 19.
Until recently, population-based data of cancer survival in Germany mostly relied on one registry covering ∼1 million people (1.3% of the German population). Here, we provide up-to-date cancer survival estimates for Germany based on data from 11 population-based cancer registries, covering 33 million people and compare them to survival estimates from the United States.
Cancer patients diagnosed in 1997-2006 were included. Period analysis was employed to calculate 5-year relative survival for 38 cancers for 2002-2006. German and USA survival rates were compared utilizing the Surveillance, Epidemiology and End Results 13 database.
Five-year relative survival >80% was observed for testicular cancer (93.5%), skin melanoma (89.4%), cancers of the prostate (89.1%) and thyroid (87.8%), Hodgkin's lymphoma (84.5%) and cancers of the breast (83.7%) and endometrium (81.0%), which together account for almost 40% of cases. For the majority of cancers, German survival estimates were close to or below those in the United States. Exceptions with higher survival in Germany were cancers of the stomach, pancreas and kidney and Hodgkin's lymphoma.
German cancer survival estimates are mostly higher than the 2000-2002 pan-European estimates. Further research is needed to investigate causes responsible for differences between German and USA cancer survival rates.
直到最近，德国的癌症生存数据主要依赖于一个覆盖约 100 万人（占德国人口的 1.3%）的登记处。在这里，我们根据来自 11 个基于人群的癌症登记处的数据，为德国提供最新的癌症生存估计，并将其与美国的生存估计进行比较。
纳入了 1997-2006 年诊断的癌症患者。采用时期分析来计算 2002-2006 年 38 种癌症的 5 年相对生存率。利用监测、流行病学和最终结果 13 数据库比较德国和美国的生存率。
观察到睾丸癌（93.5%）、皮肤黑色素瘤（89.4%）、前列腺癌（89.1%）和甲状腺癌（87.8%）、霍奇金淋巴瘤（84.5%）以及乳腺癌（83.7%）和子宫内膜癌（81.0%）的 5 年相对生存率>80%，这几种癌症加起来约占病例的 40%。对于大多数癌症，德国的生存估计接近或低于美国。在德国，胃癌、胰腺癌和肾癌以及霍奇金淋巴瘤的生存率更高。
德国癌症生存估计大多高于 2000-2002 年泛欧估计。需要进一步研究以调查导致德国和美国癌症生存率差异的原因。
