Department of Laboratory Medicine and Paik Institute for Clinical Research, Inje University College of Medicine, Busan, South Korea.
Mod Rheumatol. 2011 Dec;21(6):691-5. doi: 10.1007/s10165-011-0465-0. Epub 2011 May 20.
Leuconostoc infections are rare and usually occur in immunocompromised patients. This report describes a case of Leuconostoc lactis bacteremia in a patient with coexisting rheumatoid arthritis and tuberculosis arthritis. A disrupted gastrointestinal barrier due to gastrointestinal amyloidosis in long-standing rheumatoid arthritis and tuberculosis arthritis could be a risk factor for Leuconostoc bacteremia. Despite aggressive antibiotic treatment, the patient progressed to septic shock and multi-organ failure. The fatal course might have been caused by rapid progression of gastrointestinal pathology, which could be a risk factor for Leuconostoc bacteremia.
乳球菌感染较为罕见，通常发生于免疫功能低下的患者。本报告描述了一例合并类风湿关节炎和结核性关节炎的患者发生乳球菌血症。长期存在的类风湿关节炎和结核性关节炎导致的胃肠道淀粉样变性破坏了胃肠道屏障，可能是导致乳球菌血症的一个危险因素。尽管进行了积极的抗生素治疗，患者仍进展为感染性休克和多器官功能衰竭。快速进展的胃肠道病理可能是导致乳球菌血症的一个危险因素，这可能导致了患者的死亡。
