Fusion Sleep Medicine Program, Atlanta, GA 30024, USA.
Pediatr Clin North Am. 2011 Jun;58(3):591-620. doi: 10.1016/j.pcl.2011.03.005.
The characteristic symptoms of restless legs syndrome (RLS) have been known for hundreds of years and were first reported in medicine in the 1600s. Clinicians must consider potential mimics, comorbid, and associated conditions when evaluating children with RLS symptoms. The traditional differentiation of RLS from periodic limb movement disorder (PLMD) is noted in children as well as adults. Because current pediatric RLS research is sparse, this article provides the most up-to-date evidence-based as well as consensus opinion-based information on the subject of childhood RLS and PLMD. Prevalence, pathophysiology, diagnosis, treatment, and clinical associations are discussed.
不宁腿综合征 (RLS) 的特征性症状已经存在了数百年，并于 17 世纪首次在医学文献中报道。在评估有 RLS 症状的儿童时，临床医生必须考虑潜在的类似疾病、共病和相关疾病。RLS 与周期性肢体运动障碍 (PLMD) 的传统区分在儿童和成人中都有体现。由于目前儿科 RLS 的研究较少，本文提供了关于儿童 RLS 和 PLMD 这一主题的最新循证和基于共识的信息。本文讨论了患病率、病理生理学、诊断、治疗和临床关联。
