Adler O B, Engel A
Department of Diagnostic Radiology, Rambam Medical Center, Faculty of Medicine Haifa Technion, Israel Institute of Technology.
Rofo. 1990 Apr;152(4):460-2. doi: 10.1055/s-2008-1046904.
A retrospective study was done on 107 histologically proven cases of invasive lobular carcinoma which represent about 11.5% of the total of 934 cases of cancer of the breast. Age, breast parenchyma pattern and morphology, and radiological signs of malignancy were tabulated and correlated with the same data in ductal carcinoma. The number of false negative cases was almost twice as high as in ductal carcinoma type (19% versus 10%). In the majority of cases the patients presented a glandular or dense type of parenchyma pattern, which reduced the internal visibility. Besides spiculated masses, relatively subtle signs of malignancy, as asymmetric density and architectural distortion were relatively more frequently represented than in the ductal type of breast carcinoma. No clear-cut radiological criteria could be found pointing toward the underlying histology. Discreet clinical signs in younger patients with glandular or dense breast should alert the radiologist to the possible presence of this type of carcinoma. Due attention should be warranted to these less conspicuous signs of malignancy such as asymmetric density and architectural distortion.
对107例经组织学证实的浸润性小叶癌病例进行了回顾性研究，这些病例约占934例乳腺癌病例总数的11.5%。对年龄、乳腺实质模式和形态以及恶性肿瘤的放射学征象进行了列表，并与导管癌的相同数据进行了关联。假阴性病例数几乎是导管癌类型的两倍（19%对10%）。在大多数病例中，患者表现为腺性或致密型实质模式，这降低了内部可视性。除了毛刺状肿块外，与导管型乳腺癌相比，相对细微的恶性征象，如不对称密度和结构扭曲相对更常见。未发现指向潜在组织学的明确放射学标准。年轻的腺性或致密型乳腺患者的轻微临床体征应提醒放射科医生注意这种类型癌症的可能存在。应适当关注这些不太明显的恶性征象，如不对称密度和结构扭曲。
