Department of Ophthalmology and Visual Sciences, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
J Cataract Refract Surg. 2011 Jul;37(7):1257-62. doi: 10.1016/j.jcrs.2011.01.026. Epub 2011 May 20.
To compare a binocular free-viewing autorefractor pupillometer (WAM 5500 Binocular Accommodation Instrument) and a monocular occlusion pupillometer (Neuroptics pupillometer).
Department of Ophthalmology and Visual Sciences, Texas Tech University Health Sciences Center, Lubbock, Texas, USA.
Evaluation of diagnostic test or technology.
Normal subjects were tested under 1 lux and 7 lux ambient illumination with controlled distance fixation. The monocular occlusion pupillometer and free-viewing autorefractor pupillometer test order and eye test order were randomized. Devices were compared using Bland-Altman plots. Effects of eye test order and device test order were analyzed. The number of outliers (ie, difference ≥ 0.5 mm between devices) was tabulated.
The mean device difference (monocular pupillometer minus binocular pupillometer) was +0.51 mm ± 0.36 (SD) (range -0.20 to +1.50 mm) in right eyes and +0.27 ± 0.31 mm (SD) (range -0.30 to +1.00 mm) in left eyes at 1 lux and +0.26 ± 0.28 mm (range -0.30 to +0.90 mm) and +0.21 ± 0.24 mm (range -0.80 to +0.40 mm), respectively, at 7 lux. The outlier frequency (N = 49) at 1 lux was 23 (47%) in right eyes and 7 (14%) in left eyes and at 7 lux, 11 (22%) and 10 (20%), respectively. At all age decades, the free-viewing autorefractor underestimated dark-adapted pupil diameter. Eye test order and device order did not cause unidirectional bias.
The free-viewing pupillometer frequently disagreed with the monocular occlusion pupillometer by more than 0.5 mm. Testing the first eye with the monocular pupillometer did not induce sustained pupillary constriction that might bias results in the second eye.
比较双目自由观看自动折射计瞳孔计（WAM 5500 双目调节仪器）和单目遮盖瞳孔计。
美国德克萨斯州立大学健康科学中心眼科和视觉科学系。
诊断测试或技术的评估。
在 1 勒克斯和 7 勒克斯环境照明下，对正常受试者进行控制距离固定的测试。单目遮盖瞳孔计和自由观看自动折射计瞳孔计的测试顺序和眼测试顺序是随机的。使用 Bland-Altman 图比较设备。分析眼测试顺序和设备测试顺序的影响。记录离群值（即设备之间的差异≥0.5 毫米）的数量。
右眼在 1 勒克斯时的平均设备差异（单目瞳孔计减去双目瞳孔计）为+0.51 毫米±0.36（SD）（范围-0.20 至+1.50 毫米），左眼为+0.27±0.31 毫米（SD）（范围-0.30 至+1.00 毫米），在 7 勒克斯时分别为+0.26±0.28 毫米（范围-0.30 至+0.90 毫米）和+0.21±0.24 毫米（范围-0.80 至+0.40 毫米）。在 1 勒克斯时，右眼离群值（N=49）为 23（47%），左眼为 7（14%），在 7 勒克斯时，右眼为 11（22%），左眼为 10（20%）。在所有年龄阶段，自由观看自动折射计都低估了暗适应瞳孔直径。眼测试顺序和设备顺序没有造成单向偏差。
自由观看瞳孔计与单目遮盖瞳孔计的差异经常超过 0.5 毫米。先用单目瞳孔计测试第一只眼，不会引起第二只眼的瞳孔持续收缩，从而不会影响结果的偏倚。
