开放式自动验光仪作为瞳孔计的适用性及仪器设计影响。
Suitability of open-field autorefractors as pupillometers and instrument design effects.
作者信息
Otero Carles, Aldaba Mikel, Ferrer Oriol, Gascón Andrea, Ondategui-Parra Juan C, Pujol Jaume
机构信息
Davalor Research Center, Technical University of Catalonia, Terrassa 08222, Spain.
出版信息
Int J Ophthalmol. 2017 Apr 18;10(4):567-572. doi: 10.18240/ijo.2017.04.11. eCollection 2017.
AIM
To determine the agreement and repeatability of the pupil measurement obtained with VIP-200 (Neuroptics), PowerRef II (Plusoptix), WAM-5500 (Grand Seiko) and study the effects of instrument design on pupillometry.
METHODS
Forty patients were measured twice in low, mid and high mesopic. Repeatability was analyzed with the within-subject standard deviation (Sw) and paired -tests. Agreement was studied with Bland-Altman plots and repeated measures ANOVA. Instrument design analysis consisted on measuring pupil size with PowerRef II simulating monocular and binocular conditions as well as with proximity cues and without proximity cues.
RESULTS
The mean difference (±standard deviation) between test-retest for low, mid and high mesopic conditions were, respectively: -0.09 (±0.16), -0.05 (±0.18) and -0.08 (±0.23) mm for Neuroptics, -0.05 (±0.17), -0.12 (±0.23) and -0.17 (±0.34) mm for WAM-5500, -0.04 (±0.27), -0.13 (±0.37) and -0.11 (±0.28) mm for PowerRef II. Regarding agreement with Neuroptics, the mean difference for low, mid and high mesopic conditions were, respectively: -0.48 (±0.35), -0.83 (±0.52) and -0.38 (±0.56) mm for WAM-5500, -0.28 (±0.56), -0.70 (±0.55) and -0.61 (±0.54) mm for PowerRef II. The mean difference of binocular minus monocular pupil measurements was: -0.83 (±0.87) mm; and with proximity cues minus without proximity cues was: -0.30 (±0.77) mm.
CONCLUSION
All the instruments show similar repeat-ability. In all illumination conditions, agreement of Neuroptics with WAM-5500 and PowerRef II is not good enough, which can be partially induced due to their open field design.
目的
确定使用VIP-200（Neuroptics公司）、PowerRef II（Plusoptix公司）、WAM-5500（精工公司）进行瞳孔测量的一致性和可重复性，并研究仪器设计对瞳孔测量的影响。
方法
40例患者在低、中、高半暗视觉条件下各测量两次。采用受试者内标准差（Sw）和配对t检验分析可重复性。用Bland-Altman图和重复测量方差分析研究一致性。仪器设计分析包括使用PowerRef II在模拟单眼和双眼条件下以及有和无近距离线索的情况下测量瞳孔大小。
结果
Neuroptics公司产品在低、中、高半暗视觉条件下重测的平均差值（±标准差）分别为：-0.09（±0.16）、-0.05（±0.18）和-0.08（±0.23）mm；WAM-5500公司产品分别为：-0.05（±0.17）、-0.12（±0.23）和-0.17（±0.34）mm；PowerRef II公司产品分别为：-0.04（±0.27）、-0.13（±0.37）和-0.11（±0.28）mm。与Neuroptics公司产品相比，WAM-5500公司产品在低、中、高半暗视觉条件下的平均差值分别为：-0.48（±0.35）、-0.83（±0.52）和-0.38（±0.56）mm；PowerRef II公司产品分别为：-0.28（±0.56）、-0.70（±0.55）和-0.61（±0.54）mm。双眼瞳孔测量值减去单眼瞳孔测量值的平均差值为：-0.83（±0.87）mm；有近距离线索时的测量值减去无近距离线索时的测量值为：-0.30（±0.77）mm。
结论
所有仪器的可重复性相似。在所有光照条件下，Neuroptics公司产品与WAM-5500公司和PowerRef II公司产品的一致性不够好，这可能部分归因于它们的开放视野设计。
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