Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA.
Curr Biol. 2011 May 24;21(10):R400-2. doi: 10.1016/j.cub.2011.04.024.
Multiple studies question the necessity of transcription/translation feedback loops for the generation of circadian rhythms. New data emphasize the necessity of proteasomal degradation for circadian rhythmicity in transcriptionally competent cells.
多项研究质疑转录/翻译反馈环对于生成昼夜节律的必要性。新数据强调了蛋白酶体降解对于具有转录能力的细胞中昼夜节律的必要性。
