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[12岁患者混合性脂肪瘤致复杂脊髓栓系综合征的显微外科治疗:1例报告]

[Microsurgical treatment of complicated tethered cord resulting from mixed lipoma in a 12-year-old patient: a case report].

作者信息

Peng Lin, Xu Bo-tao

机构信息

Huiqiao Department, Nanfang Hospital, Southern Medical University, Guangzhou 510515, China.

出版信息

Nan Fang Yi Ke Da Xue Xue Bao. 2011 May;31(5):834-5.

Abstract

A 12-year-old boy was admitted for complaint of progressive urination disorder for over 2 years. Physical examination found dysesthesia in the perineal region and disappearance of anal reflex with anal relaxation and a spinal cleft in the sacrococcygeal region. Lumbosacral magnetic resonance imaging MRI showed a low-set of the spinal cord, tethered cord, spina bifida of sacral vertebrae, and meningocele combined with lipoma inside and outside of the spinal canal. Ultrasonography displayed a significantly increased residual urine volume. The diagnosis of tethered-cord syndrome resulting from mixed lipoma was thus established. During the microsurgery, the adhesions between the spinal cord, coccygeal nerve and lipoma were released with a laser scalpel, and the lipoma inside and outside of the spinal canal was excised, after which the dural defect was repaired. The patient recovered smoothly, and the urinary function was normal at the follow-up 6 months after the surgery. Spinal cord lipoma can be classified into 2 types based on the integrity of the dura mater, and in this case, a combined dural defect was found. A definite diagnosis can be derived from the clinical manifestations and MRI findings. Microsurgery remains the currently only effective treatment, and a favorable prognosis can be expected after an early surgical intervention, especially before the functional lesion of the spinal cord. The integrity of the local dura mater considerably affects the outcome of the treatment, and dural defect often leads to surgical difficulty and poor results. The key to a successful operation lies in a full release of the adhesion and avoidance of injury to the conus medullaris and cauda equina. A reoperation in case of recurrence should be carefully evaluated for its benefits.

摘要

一名12岁男孩因渐进性排尿障碍2年余入院。体格检查发现会阴部感觉障碍、肛门反射消失伴肛门松弛,骶尾部有脊柱裂。腰骶部磁共振成像(MRI)显示脊髓低位、脊髓栓系、骶椎脊柱裂、硬脊膜膨出合并椎管内外脂肪瘤。超声检查显示残余尿量显著增加。由此确诊为混合性脂肪瘤所致脊髓栓系综合征。在显微手术中,用激光刀松解脊髓、尾神经与脂肪瘤之间的粘连,切除椎管内外的脂肪瘤,然后修复硬脑膜缺损。患者恢复顺利,术后6个月随访时排尿功能正常。脊髓脂肪瘤可根据硬脑膜的完整性分为2型,本例发现合并硬脑膜缺损。根据临床表现和MRI表现可明确诊断。显微手术仍然是目前唯一有效的治疗方法,早期手术干预,尤其是在脊髓功能损害之前,有望获得良好预后。局部硬脑膜的完整性对治疗结果有很大影响,硬脑膜缺损常导致手术困难和效果不佳。手术成功的关键在于充分松解粘连,避免损伤脊髓圆锥和马尾神经。复发时再次手术应仔细评估其益处。

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