母胎液平衡与水通道蛋白：从分子到生理学。
Maternal-fetal fluid balance and aquaporins: from molecule to physiology.
机构信息
Department of Obstetrics, Guangzhou Women and Children's Medical Centre, Guangzhou Medical College, Guangzhou 510623, China.
出版信息
Acta Pharmacol Sin. 2011 Jun;32(6):716-20. doi: 10.1038/aps.2011.59. Epub 2011 May 23.
Abstract
Maternal-fetal fluid balance is critical during pregnancy, and amniotic fluid is essential for fetal growth and development. The placenta plays a key role in a successful pregnancy as the interface between the mother and her fetus. Aquaporins (AQPs) form specific water channels that allow the rapid transcellular movement of water in response to osmotic/hydrostatic pressure gradients. AQPs expression in the placenta and fetal membranes may play important roles in the maternal-fetal fluid balance.
摘要
孕妇的胎内液体平衡在孕期至关重要，而羊水对胎儿的生长和发育至关重要。胎盘在成功妊娠中起着关键作用，是母亲和胎儿之间的界面。水通道蛋白（AQPs）形成特定的水通道，使水能够快速穿过细胞，以响应渗透/静水压力梯度。胎盘和胎膜中 AQP 的表达可能在胎内液体平衡中发挥重要作用。
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