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Structure of an adsorbed dimyristoylphosphatidylcholine bilayer measured with specular reflection of neutrons.通过中子镜面反射测量的吸附二肉豆蔻酰磷脂酰胆碱双层膜的结构
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Coupling of spectrin and polylysine to phospholipid monolayers studied by specular reflection of neutrons.通过中子镜面反射研究血影蛋白和聚赖氨酸与磷脂单层的偶联。
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本文引用的文献

1
Ordering in lipid monolayers studied by synchrotron x-ray diffraction and fluorescence microscopy.通过同步加速器X射线衍射和荧光显微镜研究脂质单层中的有序排列。
Phys Rev Lett. 1987 May 25;58(21):2224-2227. doi: 10.1103/PhysRevLett.58.2224.
2
Neutron diffraction studies on selectively deuterated phospholipid bilayers.对选择性氘代磷脂双层膜的中子衍射研究。
Nature. 1978 Jan 12;271(5641):182-4. doi: 10.1038/271182a0.

中子在磷脂单分子层上的镜面反射。从膨胀相态转变为凝聚相态时单分子层结构和头部基团水合作用的变化。

Specular reflection of neutrons at phospholipid monolayers. Changes of monolayer structure and headgroup hydration at the transition from the expanded to the condensed phase state.

作者信息

Bayerl T M, Thomas R K, Penfold J, Rennie A, Sackmann E

机构信息

Technische Universität München, Physik Department E22, Garching, FRG.

出版信息

Biophys J. 1990 May;57(5):1095-8. doi: 10.1016/S0006-3495(90)82628-X.

DOI:10.1016/S0006-3495(90)82628-X
PMID:2160299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC1280815/
Abstract

The specular neutron reflection technique has been applied for the first time to study the structure and head group hydration of a phospholipid monolayer (dimyristoylphosphatidylcholine containing negatively charged phospholipids) in the condensed and expanded state. By variation of the contrast of the subphase to that of the air it is shown that at the transition from the condensed to the expanded state the carboxyl bonds of the glycerol backbone are hydrated leading to a strong structural change of the headgroup. The total monolayer thickness in the condensed state is 22.5 +/- 1 A (tilt angle 32 +/- 6 degrees) and decreases to 19.5 +/- 1 A in the expanded state. The mean molecular volume increases from 1190 +/- 50 A3 to 1250 +/- 50 A3.

摘要

镜面中子反射技术首次被用于研究处于凝聚态和膨胀态的磷脂单层（含带负电荷磷脂的二肉豆蔻酰磷脂酰胆碱）的结构和头部基团水合作用。通过改变亚相相对于空气的对比度表明，在从凝聚态转变为膨胀态时，甘油主链的羧基键发生水合，导致头部基团发生强烈的结构变化。凝聚态下整个单层的厚度为22.5±1 Å（倾斜角32±6度），在膨胀态下减小至19.5±1 Å。平均分子体积从1190±50 ų增加到1250±50 ų。