Vafa Mohammad Reza, Haghighatjoo Elham, Shidfar Farzad, Afshari Shirin, Gohari Mahmood Reza, Ziaee Amir
Nutritional Sciences, Associate Professor, President of Iranian Nutrition Society, Iran University of Medical Sciences, Tehran, Iran.
Int J Prev Med. 2011 Apr;2(2):94-100.
Fruits and vegetables may be beneficial on lipid profile of hyperlipidemic subjects. The present study was aimed to verify the effect of golden delicious apple on Lipid Profile in hyperlipidemic and overweight men.
Forty six hyperlipidemic and overweight men were randomly divided into two groups. Intervention group received 300g golden delicious apple per day for 8 weeks. Control group had the regular dietary regimen for the same period of time. Blood samples were analyzed for serum triglycerides (TG), total cholesterol (TC), low density lipoprotein-cholesterol (LDL-C), high density lipoprotein-cholesterol (HDL-C), very low density lipoprotein-cholesterol (VLDL), apolipoprotein B (Apo B), lipoprotein a (Lp a) and LDL/HDL ratio at baseline and after intervention.
Total polyphenols and fibers were 485 mg/kg and 4.03 g/100g in fresh apple respectively. After 8 weeks, significant statistical differences were observed considering the TG and VLDL levels between two groups, but no significant differences were observed regarding TC, LDL-C, HDL-C, Apo (B), Lp (a) and LDL/HDL ratio.
Consumption of Golden delicious apple may be increased serum TG and VLDL in hyperlipidemic and overweight men. We need more studies to assay the effect of apple consumption on serum TC, LDL-C, HDL-C, Apo (B), Lp (a) and LDL/HDL ratio.
水果和蔬菜可能对高脂血症患者的血脂状况有益。本研究旨在验证金冠苹果对高脂血症和超重男性血脂状况的影响。
46名高脂血症和超重男性被随机分为两组。干预组每天食用300克金冠苹果,持续8周。对照组在同一时间段采用常规饮食方案。在基线和干预后对血样进行分析,检测血清甘油三酯(TG)、总胆固醇(TC)、低密度脂蛋白胆固醇(LDL-C)、高密度脂蛋白胆固醇(HDL-C)、极低密度脂蛋白胆固醇(VLDL)、载脂蛋白B(Apo B)、脂蛋白a(Lp a)以及LDL/HDL比值。
新鲜苹果中总多酚和纤维含量分别为485毫克/千克和4.03克/100克。8周后,两组之间的TG和VLDL水平存在显著统计学差异,但在TC、LDL-C、HDL-C、Apo(B)、Lp(a)以及LDL/HDL比值方面未观察到显著差异。
食用金冠苹果可能会使高脂血症和超重男性的血清TG和VLDL升高。我们需要更多研究来测定食用苹果对血清TC、LDL-C、HDL-C、Apo(B)、Lp(a)以及LDL/HDL比值的影响。