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支气管扩张剂给药后区域性通气再分布:一例哮喘患者氙气吸入双能量 CT 研究。

Redistributed regional ventilation after the administration of a bronchodilator demonstrated on xenon-inhaled dual-energy CT in a patient with asthma.

机构信息

Department of Radiology and the Research Institute of Radiology, Asan Medical Center, University of Ulsan College of Medicine, Seoul 138-736, Korea.

出版信息

Korean J Radiol. 2011 May-Jun;12(3):386-9. doi: 10.3348/kjr.2011.12.3.386. Epub 2011 Apr 25.

DOI:10.3348/kjr.2011.12.3.386
PMID:21603299
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC3088857/
Abstract

We report here on the redistributed regional ventilation abnormalities after the administration of a bronchodilator and as seen on xenon-inhaled dual-energy CT in a patient with asthma. The improved ventilation seen in the right lower lobe and the decreased ventilation seen in the right middle lobe after the administration of a bronchodilator on xenon-inhaled dual-energy CT could explain a positive bronchodilator response on a pulmonary function test. These changes may reflect the heterogeneity of the airway responsiveness to a bronchodilator in patients with asthma.

摘要

我们在此报告一例哮喘患者吸入氙气双能 CT 后支气管扩张剂治疗后区域性通气异常再分布的病例。吸入氙气双能 CT 支气管扩张剂治疗后,右下叶通气改善,右中叶通气减少,这可以解释肺功能检查中支气管扩张剂的阳性反应。这些变化可能反映了哮喘患者气道对支气管扩张剂反应的异质性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42e/3088857/fa612c56e267/kjr-12-386-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42e/3088857/fa612c56e267/kjr-12-386-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c42e/3088857/fa612c56e267/kjr-12-386-g001.jpg

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本文引用的文献

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Radiology. 2010 Jun;255(3):790-8. doi: 10.1148/radiol.10090947.
2
Dual-energy CT: clinical applications in various pulmonary diseases.双能 CT:各种肺部疾病的临床应用。
Radiographics. 2010 May;30(3):685-98. doi: 10.1148/rg.303095101.
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Xenon ventilation CT using dual-source and dual-energy technique in children with bronchiolitis obliterans: correlation of xenon and CT density values with pulmonary function test results.
用于肺癌肿瘤轮廓描绘和异质性量化的成像技术:当前可能性概述
J Thorac Dis. 2014 Apr;6(4):319-27. doi: 10.3978/j.issn.2072-1439.2013.08.62.
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Dual-energy lung perfusion and ventilation CT in children.儿童双能肺灌注和通气 CT
Pediatr Radiol. 2013 Mar;43(3):298-307. doi: 10.1007/s00247-012-2465-4. Epub 2013 Feb 16.
5
Advanced functional thoracic imaging in children: from basic concepts to clinical applications.儿童高级功能胸部成像:从基本概念到临床应用。
Pediatr Radiol. 2013 Mar;43(3):262-8. doi: 10.1007/s00247-012-2466-3. Epub 2013 Feb 16.
应用双源和双能量技术的氙气通气 CT 检查在闭塞性细支气管炎患儿中的应用:氙气和 CT 密度值与肺功能测试结果的相关性。
Pediatr Radiol. 2010 Sep;40(9):1490-7. doi: 10.1007/s00247-010-1645-3. Epub 2010 Apr 22.
4
Xenon ventilation imaging using dual-energy computed tomography in asthmatics: initial experience.使用双能 CT 行氙气通气成像在哮喘患者中的初步经验。
Invest Radiol. 2010 Jun;45(6):354-61. doi: 10.1097/RLI.0b013e3181dfdae0.
5
Changes in regional airflow obstruction over time in the lungs of patients with asthma: evaluation with 3He MR imaging.哮喘患者肺部局部气流阻塞随时间的变化:采用³He磁共振成像进行评估
Radiology. 2009 Feb;250(2):567-75. doi: 10.1148/radiol.2502080188.
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Xenon ventilation CT with a dual-energy technique of dual-source CT: initial experience.双源CT双能量技术的氙气通气CT:初步经验。
Radiology. 2008 Aug;248(2):615-24. doi: 10.1148/radiol.2482071482.
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