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腭部小唾液腺肿瘤的外科治疗

Surgical management of minor salivary gland neoplasms of the palate.

作者信息

Moore Brian A, Burkey Brian B, Netterville James L, Butcher R Brent, Amedee Ronald G

出版信息

Ochsner J. 2008 Winter;8(4):172-80.

Abstract

OBJECTIVE

Minor salivary gland tumors are uncommon, accounting for up to 15% of salivary gland neoplasms. We describe our experience with both benign and malignant tumors of the palatal minor salivary glands, focusing on the extent of resection and options for defect reconstruction.

STUDY DESIGN

Retrospective review of medical records.

RESULTS

From 1994 to 2002, 37 patients with primary neoplasms originating in the palatal minor salivary glands were treated at a single institution. Patients ranged in age from the second to the seventh decades, with a female preponderance. Twenty-four percent of the lesions were benign. The most common malignant tumor encountered was low grade polymorphous adenocarcinoma, followed by mucoepidermoid carcinoma, and adenoid cystic carcinoma. The extent of surgical resection was dictated by tumor pathology and evidence of perineural spread, and defects were reconstructed with a variety of techniques. Postoperative complications included velopharyngeal insufficiency, flap fistulization or loss, and trismus. After 1 month to 8 years of follow-up, 1 patient has died with regional and systemic metastases.

CONCLUSIONS

Neoplasms of the minor salivary glands in the palate may be excised, with limits dictated by tumor histopathology and perineural invasion. Improved functional results may be achieved by immediately reconstructing the defects with rotational flaps, reserving free flaps for more extensive defects of the maxilla and infratemporal fossa.

摘要

目的

小唾液腺肿瘤并不常见,占唾液腺肿瘤的比例高达15%。我们描述了我们在腭部小唾液腺良性和恶性肿瘤方面的经验,重点关注切除范围和缺损重建的选择。

研究设计

对病历进行回顾性分析。

结果

1994年至2002年,一家机构共治疗了37例原发于腭部小唾液腺的肿瘤患者。患者年龄从20多岁到70多岁不等,女性居多。24%的病变为良性。最常见的恶性肿瘤是低级别多形性腺癌,其次是黏液表皮样癌和腺样囊性癌。手术切除范围取决于肿瘤病理和神经周围扩散的证据,并采用多种技术重建缺损。术后并发症包括腭咽闭合不全、皮瓣瘘或皮瓣坏死以及牙关紧闭。经过1个月至8年的随访,1例患者因局部和全身转移死亡。

结论

腭部小唾液腺肿瘤可进行切除,切除范围受肿瘤组织病理学和神经侵犯情况的限制。通过使用旋转皮瓣立即重建缺损,将游离皮瓣留用于上颌骨和颞下窝更广泛的缺损,可取得更好的功能效果。

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