Department of Organic Chemistry, University of Geneva, Quai Ernest Ansermet, 30, 1211, Geneva 4, Switzerland.
Chem Commun (Camb). 2011 Jul 7;47(25):7212-4. doi: 10.1039/c1cc11967b. Epub 2011 May 23.
An unprecedented intermolecular iminium/enamine Michael addition on enals has been developed by taking advantage of the high reactivity of vinyl sulfones. This powerful organocascade allows for the rapid construction of attractive synthons in high enantioselectivities (typically 99% ee).
利用乙烯砜的高反应活性，开发了一种前所未有的醛亚胺/烯胺迈克尔加成的分子间反应。这种强大的有机级联反应能够以高对映选择性（通常为 99%ee）快速构建有吸引力的合成子。
