Lupi Omar, Rezende Ludimila, Zangrando Mariane, Sessim Marlene, Silveira Cíntia Botelho, Sepulcri Maria Anísia Silva, Duarte Deilton Junior, Cardim Priscilla, Fernandes Mário Meyer, Santos Omar da Rosa
Dermatology Service of the General Polyclinic of Rio de Janeiro and at the Internal Medicine Service (10th Ward) - School of Medicine and Surgery, Federal University of Rio de Janeiro State (UNIRIO) - Rio de Janeiro (RJ), Brazil.
An Bras Dermatol. 2011 Mar-Apr;86(2):319-26. doi: 10.1590/s0365-05962011000200015.
The prevalence of chronic kidney disease has increased over the last years. The effects of this disease are complex and may lead to dysfunction of multiple organs, including the skin, with most patients presenting with at least one dermatologic alteration. Sometimes these symptoms can be the first clear sign of kidney disease. This article discusses the skin manifestations related to severe renal impairment or end-stage renal disease (ESRD), which are divided into nonspecific and specific, and reviews the clinical features, etiopathogenesis and therapeutic options for these dermatoses. Early recognition and treatment reduce morbidity and improve these patients' quality of life.
在过去几年中，慢性肾脏病的患病率有所上升。这种疾病的影响是复杂的，可能导致包括皮肤在内的多个器官功能障碍，大多数患者至少出现一种皮肤改变。有时这些症状可能是肾脏疾病的首个明显迹象。本文讨论了与严重肾功能损害或终末期肾病（ESRD）相关的皮肤表现，这些表现分为非特异性和特异性两类，并综述了这些皮肤病的临床特征、病因发病机制和治疗选择。早期识别和治疗可降低发病率并改善这些患者的生活质量。
