Microbial Technology Laboratory, Department of Microbiology, Guru Nanak Dev University, Amritsar 143005, India.
Appl Biochem Biotechnol. 2011 Sep;165(2):639-51. doi: 10.1007/s12010-011-9282-3. Epub 2011 May 21.
Fungal isolates (Aspergillus wentii 1, A. wentii 2, Penicillium citrinum, Penicillium granulatum) were selected to study their in vitro antioxidant potential by various assay procedures. Czapek-Dox's medium was selected for the growth of fungi as it supported the best antioxidant activity based on their EC(50) values, P. citrinum was the best followed by P. granulatum, A. wentii 1, and A. wentii 2. The chromatographic analyses showed several compounds possessing antioxidant activity in the fungal extracts. Two such compounds were partially purified from P. citrinum which demonstrated potent antioxidant activity, equally effective or better than some of the standard antioxidants.
选择真菌分离株（构巢曲霉 1、构巢曲霉 2、青霉柠檬酸、青霉球状变种），通过各种测定程序研究其体外抗氧化潜力。选择察氏培养基来培养真菌，因为根据其 EC（50）值，该培养基最能支持抗氧化活性，青霉柠檬酸表现出最好的抗氧化活性，其次是青霉球状变种、构巢曲霉 1 和构巢曲霉 2。色谱分析显示真菌提取物中含有几种具有抗氧化活性的化合物。从青霉柠檬酸中部分纯化了两种具有抗氧化活性的化合物，其抗氧化活性与一些标准抗氧化剂相当或更好。
