Kurita-Tashima S, Tobimatsu S, Nakayama-Hiromatsu M, Kato M
Department of Clinical Neurophysiology, Faculty of Medicine, Kyushu University, Fukuoka, Japan.
Invest Ophthalmol Vis Sci. 1992 Jul;33(8):2423-8.
To demonstrate that the frontal negative potential (N100) does exist in response to pattern-reversal visual stimulation and its independence of the dipole source from the major occipital positive potential (P100), modifications of P100 and N100 with changes in the check size, contrast, and luminance of the stimulus pattern were studied in healthy subjects. Eight different check sizes (10-90 min of arc), eight different contrast levels (10-85%), and six different luminance levels (11-180 cd/m2) were used. Changing the stimulus conditions modified the latencies and amplitudes of P100 and N100 in different ways. P100 latency had a band pass spatial tuning function against check size; N100 latency did not. P100 was sensitive to changes in contrast and luminance; N100 was less dependent on these parameters. These findings suggest the existence of different physiologic properties for N100. Consequently, frontal negativity is considered to be independent of P100.
为了证明在模式反转视觉刺激下额部负电位（N100）确实存在，以及其偶极子源与主要枕部正电位（P100）的独立性，我们在健康受试者中研究了刺激模式的方格大小、对比度和亮度变化对P100和N100的影响。使用了八种不同的方格大小（10 - 90分视角）、八种不同的对比度水平（10 - 85%）和六种不同的亮度水平（11 - 180 cd/m²）。改变刺激条件以不同方式改变了P100和N100的潜伏期和波幅。P100潜伏期针对方格大小具有带通空间调谐功能；N100潜伏期则没有。P100对对比度和亮度变化敏感；N100对这些参数的依赖性较小。这些发现提示N100存在不同的生理特性。因此，额部负电位被认为独立于P100。
