Niemeier Janet P, Kreutzer Jeffrey S, Marwitz Jennifer H, Gary Kelli W, Ketchum Jessica M
Department of Physical Medicine and Rehabilitation,Virginia Commonwealth University, Richmond, VA 23298-0542, USA.
Brain Inj. 2011;25(7-8):680-90. doi: 10.3109/02699052.2011.573520. Epub 2011 May 23.
To evaluate the effectiveness of a brief acute neurobehavioural intervention, the First Steps Acute Neurobehavioural and Cognitive Intervention (FANCI), with persons who have traumatic brain injury (TBI).
Prospective, controlled, repeated measures design.
Seventy-two patients in acute TBI rehabilitation participated either as FANCI subjects or as control participants who watched videos to control for time and attention. Outcome measures included the Neurobehavioural Rating Scale-Revised (NRS-R), Functional Independence Measure (FIM™), a FANCI Learning Assessment (LA) and the Satisfaction with Life Scale (SWLS).
In comparison with controls, FANCI participants had significantly greater neurobehavioural (cognitive, emotional and behavioural) as well as FIM motor improvements. Significantly greater learning occurred and persisted over time for FANCI subjects as compared to controls. Pre-treatment cognitive and neurobehavioural status, length of coma and number of sessions completed were moderating variables for functional and cognitive outcomes.
Persons with TBI can benefit from comprehensive, manualized neurobehavioural interventions, over and above standard rehabilitation care, even during the acute phase of recovery.
评估一种简短的急性神经行为干预措施——第一步急性神经行为与认知干预(FANCI)对创伤性脑损伤(TBI)患者的有效性。
前瞻性、对照、重复测量设计。
72名急性TBI康复患者参与研究,他们要么作为FANCI受试者,要么作为观看视频以控制时间和注意力的对照参与者。结果测量指标包括修订版神经行为评定量表(NRS-R)、功能独立性测量量表(FIM™)、FANCI学习评估(LA)以及生活满意度量表(SWLS)。
与对照组相比,FANCI参与者在神经行为(认知、情感和行为)以及FIM运动功能方面有显著更大的改善。与对照组相比,FANCI受试者随着时间推移出现并持续存在显著更多的学习成果。治疗前的认知和神经行为状态、昏迷时长以及完成的疗程数是功能和认知结果的调节变量。
即使在恢复的急性期,TBI患者除了接受标准康复护理外,还能从全面的、手册化的神经行为干预中获益。