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[应用纺锤菌素沉淀试验检测儿童脑膜炎患者可溶性纤维蛋白单体复合物]

[Detection of soluble fibrin monomer complexes by the netropsin precipitation test in childhood meningitis].

作者信息

Lutze G, Mittler U, Schulze M, Urbahn H

机构信息

Institut für Klinische Chemie und Laboratoriumsdiagnostik, Medizinischen Akademie Magdeburg.

出版信息

Z Med Lab Diagn. 1990;31(2):97-103.

PMID:2160762
Abstract

During a period of two years children with abacterial meningitis as well as bacterial meningitis were examined before treatment and later during disease. The new Netropsin praecipitation test according to Funke and coworkers was used to detect soluble fibrin monomer complexes. Only in a few cases of abacterial meningitis, but in the majority of cases with bacterial meningitis, a positive result had been shown. Excessive increase had been found in Waterhouse-Friderichsen syndrome. According to our results of coagulation tests we conclude 1. the ethanol gelation test is out-of-date, 2. the heparin treatment in bacterial meningitis is further indicated.

摘要

在两年时间里,对患有无菌性脑膜炎和细菌性脑膜炎的儿童在治疗前及患病期间进行了检查。采用了Funke及其同事提出的新的鱼精蛋白沉淀试验来检测可溶性纤维蛋白单体复合物。仅在少数无菌性脑膜炎病例中呈阳性结果,但在大多数细菌性脑膜炎病例中呈阳性。在华-弗综合征中发现有过度增加。根据我们的凝血试验结果,我们得出结论:1. 乙醇凝胶试验已过时;2. 细菌性脑膜炎仍需进一步进行肝素治疗。

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