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[肝转移瘤的检测与特征分析]

[Detection and characterization of liver metastases].

作者信息

Weskott H-P

机构信息

Zentrale Sonographieabteilung, Klinikum Siloah, KRH, Roesebeckstr 15, 30559 Hannover.

出版信息

Radiologe. 2011 Jun;51(6):469-74. doi: 10.1007/s00117-010-2100-z.

DOI:10.1007/s00117-010-2100-z
PMID:21607764
Abstract

Since the advent of second generation ultrasound (US) contrast agents, ultrasound has caught up with other imaging modalities for the detection and characterization of liver metastases and as a result of its high temporal and spatial resolution it can in some cases even be superior to computed tomography (CT) and magnetic resonance imaging (MRI). Many studies have demonstrated a sensitivity and specificity of over 90%. Due to its high temporal resolution contrast-enhanced US (CEUS) is capable of detecting even a very short duration of hyper-enhancement during the arterial phase. Radiation protection and lack of adverse effects on renal or thyroid function are additional arguments why CEUS should be recommended as the first imaging modality in the evaluation of hepatic metastases in cases of favorable scanning conditions.

摘要

自第二代超声(US)造影剂问世以来,超声在肝转移瘤的检测和特征描述方面已赶上其他成像方式,并且由于其高时间和空间分辨率,在某些情况下甚至优于计算机断层扫描(CT)和磁共振成像(MRI)。许多研究已证明其敏感性和特异性超过90%。由于具有高时间分辨率,超声造影增强(CEUS)甚至能够检测到动脉期极短时间的高增强。辐射防护以及对肾脏或甲状腺功能无不良影响是在扫描条件良好的情况下推荐CEUS作为肝转移瘤评估的首选成像方式的额外理由。

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本文引用的文献

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Contrast-enhanced ultrasound for the characterization of focal liver lesions--diagnostic accuracy in clinical practice (DEGUM multicenter trial).超声造影用于肝脏局灶性病变的特征性诊断——临床实践中的诊断准确性(德国超声医学学会多中心试验)
Ultraschall Med. 2008 Oct;29(5):499-505. doi: 10.1055/s-2008-1027806.
2
Contrast-enhanced ultrasonography in patients with colorectal liver metastases after chemotherapy.化疗后结直肠癌肝转移患者的超声造影检查
Ultraschall Med. 2008 Sep;29 Suppl 4:S203-9. doi: 10.1055/s-2008-1027795. Epub 2008 Oct 2.
3
Benefits of contrast-enhanced sonography for the detection of liver lesions: comparison with histologic findings.
超声造影在肝脏病变检测中的优势:与组织学结果的比较
AJR Am J Roentgenol. 2008 Mar;190(3):683-90. doi: 10.2214/AJR.07.2295.
4
Guidelines and good clinical practice recommendations for contrast enhanced ultrasound (CEUS) - update 2008.超声造影(CEUS)指南及临床实践建议 - 2008年更新版
Ultraschall Med. 2008 Feb;29(1):28-44. doi: 10.1055/s-2007-963785.
5
Real time contrast enhanced ultrasonography in detection of liver metastases from gastrointestinal cancer.实时超声造影在检测胃肠道癌肝转移中的应用
BMC Cancer. 2007 Sep 3;7:171. doi: 10.1186/1471-2407-7-171.
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Enhancement patterns of focal liver masses: discordance between contrast-enhanced sonography and contrast-enhanced CT and MRI.肝脏局灶性肿块的强化模式:超声造影与CT及MRI增强扫描之间的不一致性
AJR Am J Roentgenol. 2007 Jul;189(1):W7-W12. doi: 10.2214/AJR.06.1060.
7
Contrast-enhanced ultrasonography in diagnosing liver metastases.超声造影在诊断肝转移瘤中的应用
Med Sci Monit. 2007 May;13 Suppl 1:111-5.
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New perspectives for the use of contrast-enhanced liver ultrasound in clinical practice.临床实践中使用肝脏超声造影的新视角。
Dig Liver Dis. 2007 Feb;39(2):187-95. doi: 10.1016/j.dld.2006.08.008. Epub 2007 Jan 8.
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The value of contrast enhanced ultrasonography in detection of liver metastases from colorectal cancer: a prospective double-blinded study.对比增强超声检查在检测结直肠癌肝转移中的价值:一项前瞻性双盲研究。
Eur J Radiol. 2007 May;62(2):302-7. doi: 10.1016/j.ejrad.2006.11.033. Epub 2006 Dec 27.
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J Clin Oncol. 2006 Aug 20;24(24):3939-45. doi: 10.1200/JCO.2006.05.8727.