[细菌对抗生素耐药性的分子与流行病学基础]
[Molecular and epidemiological bases of bacterial resistance to antibiotics].
作者信息
Guillot J F
机构信息
INRA, Station de pathologie aviaire et de parasitologie, CR de Tours-Nouzilly, Monnaie, France.
出版信息
Ann Rech Vet. 1990;21(1):1-11.
PMID:2160785
Abstract
The emergence of resistance to antibiotics is related to the genetic determinants of microbial resistance. The characteristics and properties of chromosomal mutations, plasmids, transposons and the various mechanisms of resistance are described. The range of bacterial and genetic exchanges in determining the epidemic spread of resistance to an antibiotic are illustrated and discussed.
摘要
抗生素耐药性的出现与微生物耐药性的遗传决定因素有关。本文描述了染色体突变、质粒、转座子的特征和性质以及各种耐药机制。文中阐述并讨论了细菌和基因交换在决定抗生素耐药性流行传播方面的范围。
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