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Phorbol myristate acetate enhances adenylate cyclase activity in human polymorphonuclear leukocytes.

作者信息

Rebut-Bonneton C, Demignon J, Sourbier P

机构信息

U 262 INSERM, Paris, France.

出版信息

Horm Metab Res. 1990 Mar;22(3):175-8. doi: 10.1055/s-2007-1004877.

Abstract

The putative role of protein phosphorylation in modulating adenylate cyclase activity in polymorphonuclear neutrophil membranes was assessed using phorbol myristate acetate (PMA) to stimulate the activity of protein kinase C. PMA was demonstrated to enhance the adenylate cyclase activity stimulated by isoproterenol.

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