Xu Hai-feng, Yang Ren-jie, Chen Hui, Zhu Xu
Key Laboratory of Carcinogenesis and Translational Research(Ministry of Education), Peking University School of Oncology, Beijing Cancer Hospital & Institute, Beijing 100142, China.
Zhonghua Yi Xue Za Zhi. 2011 Apr 19;91(15):1061-3.
To observe and compare the revasculation rate after embolization of hepatic artery-portal vein fistula (APVF) by gelatin sponge versus gelatin sponge with lipiodol.
The clinical data of 51 patients were retrospectively analyzed. They were divided into Groups A and B. APVF was embolized by gelatin sponge alone in Group A and gelatin sponge with lipiodol in Group B. Then the investigators observed and compared the revasculation rate of hepatic artery-portal vein fistula at Days 30 - 40 and 60 - 70 post-embolization respectively.
There was no statistical difference in age, gender, pathological types and hepatic functions before intervention between Groups A and B. One of 28 APVF sites was embolized unsuccessfully in Group A while all APVF cases were embolized successfully in Group B. The revasculation rate of hepatic APVF were 70.37% and 46.15% at Days 30 - 40 post-embolization in Groups A and B respectively (χ(2) = 4.25, P = 0.039, chi-square test); the revasculation rates of APVF were 92.59% and 88.46% respectively at Days 60 - 70 post-embolization (P = 0.67).
Interventional therapy of hepatic APVF by gelatin sponge and lipiodol is a safe method of reducing the short-term revasculation rate. It may be employed in clinical practices to save precious time for controlling hepatic malignant tumors.
观察并比较明胶海绵与碘化油混合明胶海绵栓塞肝动脉门静脉瘘（APVF）后的再通率。
回顾性分析51例患者的临床资料。将其分为A组和B组。A组单纯用明胶海绵栓塞APVF，B组用碘化油混合明胶海绵栓塞。然后分别观察并比较栓塞后30 - 40天和60 - 70天肝动脉门静脉瘘的再通率。
A组和B组干预前在年龄、性别、病理类型及肝功能方面无统计学差异。A组28个APVF部位中有1个栓塞失败，而B组所有APVF病例均栓塞成功。栓塞后30 - 40天，A组和B组肝APVF的再通率分别为70.37%和46.15%（χ(2)=4.25，P = 0.039，卡方检验）；栓塞后60 - 70天，APVF的再通率分别为92.59%和88.46%（P = 0.67）。
明胶海绵联合碘化油介入治疗肝APVF是降低短期再通率的安全方法。可应用于临床实践，为控制肝脏恶性肿瘤节省宝贵时间。
