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青光眼药物治疗依从性、滴眼技术与视野缺损严重程度之间的关系。

The relationship between glaucoma medication adherence, eye drop technique, and visual field defect severity.

机构信息

Division of Pharmaceutical Outcomes and Policy, Eshelman School of Pharmacy, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina 27599-7590, USA.

出版信息

Ophthalmology. 2011 Dec;118(12):2398-402. doi: 10.1016/j.ophtha.2011.05.013.

Abstract

OBJECTIVE

The purpose of the study was to examine (1) how patient adherence and eye drop technique were associated with visual field defect severity and (2) how general glaucoma adherence self-efficacy and eye drop technique self-efficacy were related to visual field defect severity.

DESIGN

Cross-sectional study conducted at a single private practice site.

PARTICIPANTS

Patients using eye drops for their glaucoma.

METHODS

Subject adherence to glaucoma medications through Medication Events Monitoring System (MEMS) devices were measured, and eye drop instillation technique was assessed by video recording. General glaucoma medication adherence self-efficacy was measured using a 10-item scale, and eye drop technique self-efficacy was measured using a 6-item scale. Multivariate logistic regression was used to analyze the data.

MAIN OUTCOME MEASURES

Visual field defect severity.

RESULTS

Patients who were less than 80% adherent according to the MEMS devices were significantly more likely to have worse defect severity. Patients with lower scores on the general glaucoma medication adherence self-efficacy scale also were significantly more likely to have worse defect severity. Eye drop technique and eye drop technique self-efficacy were not related significantly to visual field defect severity.

CONCLUSIONS

Eye care providers need to assess patient adherence and to work with those patients with poor adherence to find ways to improve their ability and self-efficacy in using their glaucoma medications.

FINANCIAL DISCLOSURE(S): Proprietary or commercial disclosure may be found after the references.

摘要

目的

本研究旨在探讨(1)患者的依从性和滴眼技术与视野缺损严重程度的关系,以及(2)一般青光眼用药依从自我效能感和滴眼技术自我效能感与视野缺损严重程度的关系。

设计

在一个私人诊所进行的横断面研究。

参与者

使用滴眼剂治疗青光眼的患者。

方法

通过 Medication Events Monitoring System(MEMS)设备测量受试者对青光眼药物的依从性,通过视频记录评估滴眼技术。使用 10 项量表测量一般青光眼用药依从自我效能感,使用 6 项量表测量滴眼技术自我效能感。采用多变量逻辑回归分析数据。

主要观察指标

视野缺损严重程度。

结果

根据 MEMS 设备,不到 80%依从的患者视野缺损严重程度明显更差。一般青光眼用药依从自我效能感量表得分较低的患者视野缺损严重程度也明显更差。滴眼技术和滴眼技术自我效能感与视野缺损严重程度无显著相关性。

结论

眼保健提供者需要评估患者的依从性,并与依从性差的患者合作,寻找提高他们使用青光眼药物的能力和自我效能感的方法。

利益冲突披露

参考文献之后可能会发现专有或商业披露。

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