抗拓扑异构酶I和抗着丝粒自身抗体的IgG、IgM和IgA同种型。
The IgG, IgM, and IgA isotypes of anti-topoisomerase I and anticentromere autoantibodies.
作者信息
Hildebrandt S, Weiner E, Senécal J L, Noell S, Daniels L, Earnshaw W C, Rothfield N F
机构信息
Department of Medicine, University of Connecticut School of Medicine, Farmington 06032.
出版信息
Arthritis Rheum. 1990 May;33(5):724-7. doi: 10.1002/art.1780330515.
We studied the expression of IgG, IgM, and IgA autoantibodies in the anti-topoisomerase I and anticentromere immune responses by enzyme-linked immunosorbent assay, immunoblotting, and immunofluorescence. While IgG autoantibodies were most common, IgA autoantibodies were also frequently found, but IgM autoantibodies were rare. This is the first report of IgA autoantibodies in scleroderma.
我们通过酶联免疫吸附测定、免疫印迹和免疫荧光研究了抗拓扑异构酶I和抗着丝粒免疫反应中IgG、IgM和IgA自身抗体的表达。虽然IgG自身抗体最为常见，但也经常发现IgA自身抗体，而IgM自身抗体则很罕见。这是硬皮病中IgA自身抗体的首次报道。
Zotero 插件