Lee Cheong J, Morasch Mark D
Division of Vascular Surgery, Northwestern University, Chicago, IL 60611, USA.
Expert Rev Cardiovasc Ther. 2011 May;9(5):575-8. doi: 10.1586/erc.11.54.
Symptomatic disease of the vertebrobasilar circulation is often underdiagnosed and undertreated. In recent years, endovascular revascularization of vertebral artery stenosis has been heralded as a less invasive treatment option in comparison to open surgery, with the inherent risk of morbidity. Although a growing number of case reports and small nonrandomized case series suggest that endovascular intervention in the posterior circulation may be safe and technically feasible, the safety and benefit of angioplasty and stent placement in cases of symptomatic vertebral disease, as compared with the most effective medical therapy, remains to be elucidated.
椎基底动脉循环的症状性疾病常常诊断不足且治疗不充分。近年来，与开放性手术相比，椎动脉狭窄的血管内血运重建术被视为一种侵入性较小的治疗选择，但存在内在的发病风险。尽管越来越多的病例报告和小型非随机病例系列表明，后循环的血管内介入治疗可能是安全的且在技术上可行，但与最有效的药物治疗相比，有症状的椎动脉疾病行血管成形术和支架置入术的安全性和益处仍有待阐明。
