Department of Dermatology, Venereology and Allergy, University Clinic Schleswig-Holstein, Campus Kiel, Germany.
J Dtsch Dermatol Ges. 2011 Sep;9(9):678-80. doi: 10.1111/j.1610-0387.2011.07708.x. Epub 2011 May 25.
Antimicrobial peptides represent evolutionary ancient molecules whose importance became evident within the last years. These highly effective peptides protect the skin and other epithelia against infection and form a fast acting "chemical barrier" also regulating the normal flora of the skin and mucosa. In the Department of Dermatology, University Hospital Kiel, various antimicrobial peptides have been discovered, characterized and investigated in healthy persons as well as in different skin diseases. Everyday clinical observations formed the background for several interesting hypotheses and findings.
抗菌肽是进化上古老的分子，其重要性在近几年变得明显。这些高效的肽保护皮肤和其他上皮组织免受感染，并形成快速作用的“化学屏障”，还能调节皮肤和黏膜的正常菌群。在基尔大学医院皮肤科，已经发现、鉴定和研究了各种抗菌肽，包括在健康人群和不同皮肤疾病中的情况。日常临床观察为一些有趣的假设和发现提供了背景。
