Department of Orthopaedic Surgery, University of Toyama, Toyama 930-0194, Japan.
Oncol Rep. 2011 Sep;26(3):711-5. doi: 10.3892/or.2011.1326. Epub 2011 May 26.
The occurrence of primary extraskeletal Ewing's sarcoma (EES) of the spinal epidural space has been rarely reported in the literature. The clinical, radiologic and pathologic features of a case of EES occurring in the thoracic epidural space are presented. A 37-year-old woman presented with a one-year history of back pain. Magnetic resonance imaging demonstrated an epidural mass at the T8-9 level. Laminectomy and partial resection of the tumor were performed. The differential diagnosis of a spinal epidural mass is broad. Histopathological and molecular cytogenetic examinations confirmed an EES arising from the thoracic epidural space. Despite receiving both chemotherapy and radiotherapy, the patient died of respiratory insufficiency due to medulla oblongata metastasis 22 months after the initial consultation. Awareness of this entity will allow this rare diagnosis to be considered and facilitate appropriate management. A review of the literature on spinal epidural EES is also presented.
原发性骨外尤因肉瘤（EES）发生于椎管硬膜外腔的情况在文献中鲜有报道。本文报告了一例发生于胸段硬膜外腔的 EES 的临床、影像学和病理学特征。一名 37 岁女性因背痛 1 年就诊。磁共振成像显示 T8-9 水平硬膜外肿块。行椎板切除术和肿瘤部分切除术。椎管硬膜外肿块的鉴别诊断广泛。组织病理学和分子细胞遗传学检查证实该肿瘤源自胸段硬膜外腔。尽管接受了化疗和放疗，但患者在初始就诊后 22 个月因延髓转移导致呼吸功能不全而死亡。了解该疾病可考虑此罕见诊断，并有助于进行适当的治疗。本文还对文献中关于脊髓硬膜外 EES 的内容进行了复习。
