Ayhan A, Ergeneli M H, Yüce K, Yapar E G, Kişnişçi A H
Department of Obstetrics and Gynecology, Faculty of Medicine, Hacettepe University, Ankara, Turkey.
J Reprod Med. 1990 May;35(5):522-4.
Forty-nine women who had received chemotherapy for gestational trophoblastic disease subsequently became pregnant a total of 65 times. Of these 65 pregnancies, 42 (64.7%) terminated in term births, 4 (6.1%) in premature births, 1 (1.5%) in stillbirth, 8 (2.3%) in spontaneous abortion and 7 (10.8%) in elective abortion, while 3 patients (4.6%) had repeat molar pregnancies. No congenital malformations or obstetric complications were observed. Treatment of gestational trophoblastic disease with chemotherapy is compatible with the preservation of fertility and is not associated with any increase in congenital fetal malformations.
49名曾接受过妊娠滋养细胞疾病化疗的女性随后共怀孕65次。在这65次妊娠中，42次（64.7%）足月分娩，4次（6.1%）早产，1次（1.5%）死产，8次（2.3%）自然流产，7次（10.8%）人工流产，而3名患者（4.6%）再次发生葡萄胎妊娠。未观察到先天性畸形或产科并发症。用化疗治疗妊娠滋养细胞疾病与保留生育能力是相容的，并且与先天性胎儿畸形的增加无关。
