通过奥弗豪泽效应成像对注射自由基进行体内检测。
In vivo detection of injected free radicals by Overhauser effect imaging.
作者信息
Grucker D
机构信息
Institut de Physique Biologique, UA du CNRS 1173, Faculté de Medecine, Université Louis Pasteur, Strasbourg, France.
出版信息
Magn Reson Med. 1990 Apr;14(1):140-7. doi: 10.1002/mrm.1910140113.
PMID:2161981
Abstract
Proton dynamical polarization is a method which unites the advantages of continuous wave ESR sensitivity and pulsed NMR imaging in order to localize free radicals. Injected nitroxide has been imaged for the first time in living rats. The high sensitivity of this method to oxygen is demonstrated.
摘要
质子动态极化是一种结合了连续波电子顺磁共振灵敏度和脉冲核磁共振成像优势的方法，用于定位自由基。首次在活体大鼠中对注射的氮氧化物进行了成像。证明了该方法对氧气具有高灵敏度。
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