Miura Y, Utsumi H, Hamada A
Department of Health Chemistry, School of Pharmaceutical Sciences, Showa University, Tokyo, Japan.
Biochem Biophys Res Commun. 1992 Feb 14;182(3):1108-14. doi: 10.1016/0006-291x(92)91846-i.
Effects of inspired oxygen concentration on metabolism of nitroxide radical were measured in whole mice by using in vivo ESR. Oxygen concentration influenced spin-clearance of nitroxide differently in abdomen and head, suggesting that either O2 concentrations or metabolic mechanisms of nitroxide in the two domains were different.
通过体内电子自旋共振(ESR)测量了吸入氧浓度对全小鼠体内氮氧化物自由基代谢的影响。氧浓度对腹部和头部氮氧化物的自旋清除有不同影响,这表明这两个区域的氧浓度或氮氧化物的代谢机制有所不同。