评估印度三个地区的随访情况，以及癌症病例确定的完整性和准确性。
Assessment of follow-up, and the completeness and accuracy of cancer case ascertainment in three areas of India.
机构信息
Regional Cancer Center, Trivandrum, Kerala, India.
出版信息
Cancer Epidemiol. 2011 Aug;35(4):334-41. doi: 10.1016/j.canep.2011.03.006. Epub 2011 May 28.
BACKGROUND
A prospective study of diet and cancer has not been conducted in India; consequently, little is known regarding follow-up rates or the completeness and accuracy of cancer case ascertainment.
METHODS
We assessed follow-up in the India Health Study (IHS; 4671 participants aged 35-69 residing in New Delhi, Mumbai, or Trivandrum). We evaluated the impact of medical care access and relocation, re-contacted the IHS participants to estimate follow-up rates, and conducted separate studies of cancer cases to evaluate registry coverage (604 cases in Trivandrum) and the accuracy of self- and proxy-reporting (1600 cases in New Delhi and Trivandrum).
RESULTS
Over 97% of people reported seeing a doctor and 85% had lived in their current residence for over six years. The 2-year follow-up rate was 91% for Trivandrum and 53% for New Delhi. No cancer cases were missed among public institutions participating in the surveillance program in Trivandrum during 2003-2004; but there are likely to be unmatched cases (ranging from 5 to 13% of total cases) from private hospitals in the Trivandrum registry, as there are no mandatory reporting requirements. Vital status was obtained for 36% of cancer cases in New Delhi as compared to 78% in Trivandrum after a period of 4 years.
CONCLUSIONS
A prospective cohort study of cancer may be feasible in some centers in India with active follow-up to supplement registry data. Inclusion of cancers diagnosed at private institutions, unique identifiers for individuals, and computerized medical information would likely improve cancer registries.
背景
在印度，尚未开展针对饮食与癌症的前瞻性研究；因此，人们对癌症病例随访率、癌症病例确定的完整性和准确性知之甚少。
方法
我们评估了印度健康研究（IHS；4671 名年龄在 35-69 岁之间的参与者，居住在新德里、孟买或特里凡得琅）的随访情况。我们评估了医疗保健获取和搬迁的影响，重新联系了 IHS 参与者以估计随访率，并对癌症病例进行了单独的研究，以评估登记处的覆盖范围（特里凡得琅有 604 例）以及自我报告和代理报告的准确性（新德里和特里凡得琅有 1600 例）。
结果
超过 97%的人报告看过医生，85%的人在目前的住所居住超过六年。特里凡得琅的 2 年随访率为 91%，新德里的随访率为 53%。在 2003-2004 年期间，参与特里凡得琅监测计划的公共机构没有遗漏任何癌症病例；但特里凡得琅登记处可能存在未匹配的病例（占总病例的 5%至 13%），因为私人医院没有强制性报告要求。在四年后，新德里有 36%的癌症病例可以获得生存状态，而特里凡得琅则有 78%。
结论
在印度的一些中心，通过积极随访来补充登记处数据，开展癌症前瞻性队列研究是可行的。纳入私营机构诊断的癌症、个人的独特标识符和计算机化的医疗信息，可能会提高癌症登记处的水平。
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