A mouse attenuated mutant of Junin virus with an altered envelope glycoprotein.
作者信息
Scolaro L A, Mersich S E, Damonte E B
机构信息
Laboratorio de Virología, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Argentina.
出版信息
Arch Virol. 1990;111(3-4):257-62. doi: 10.1007/BF01311059.
PMID:2162164
Abstract
The XJC13 strain of Junin virus (JV) and the mouse-attenuated mutant C167 showed different GP38 peptide mapping after limited proteolysis with ficin and papain; viral infectivity of both viruses also exhibited a different susceptibility to protease treatment. A correlation between envelope glycoprotein alteration and JV virulence in neonatal mice is proposed.
摘要
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