Negri B, Haberl R, Neubert U, Wilmes E
Klinik und Poliklinik für Hals-Nasen-Ohrenkranke, Ludwig-Maximilians-Universität München.
Laryngorhinootologie. 1990 May;69(5):281-4. doi: 10.1055/s-2007-998190.
Cutaneous leishmaniasis is a parasitic infection which is especially endemic in the southern parts of Europe, in several regions of Africa, and in South and Central America. Whether treatment is necessary or not depends on the virulence of the germ, the infection's localization, and the host's immunological reaction. Because of the high rate of recidivation and the large number of undesirable side-effects of systemic chemotherapy of localized cutaneous leishmaniasis, several methods of local therapy have been tested. This case report demonstrates one of several approaches to the local treatment of this disease. Despite progress in this field, cutaneous leishmaniasis will continue to be a considerable medical and sociopolitical problem, because successful treatments in under-developed countries must be highly efficient, cost little, be easy to administer, and have a low rate of undesirable side-effects.
皮肤利什曼病是一种寄生虫感染,在欧洲南部、非洲的几个地区以及南美洲和中美洲尤为流行。是否需要治疗取决于病原体的毒力、感染的部位以及宿主的免疫反应。由于局部皮肤利什曼病全身化疗的复发率高且有大量不良副作用,人们已经测试了几种局部治疗方法。本病例报告展示了针对该疾病局部治疗的几种方法之一。尽管该领域取得了进展,但皮肤利什曼病仍将是一个相当严重的医学和社会政治问题,因为在欠发达国家成功的治疗方法必须高效、成本低、易于实施且不良副作用发生率低。