Zlotogorski A, Gilead L, Jonas F, Horev L, Klaus S N
Department of Dermatology, Hadassah University Hospital, Jerusalem, Israel.
J Eur Acad Dermatol Venereol. 1998 Jul;11(1):32-6.
Cutaneous South American leishmaniasis is caused by several species of leishmaniasis. Lack of appropriate treatment may lead to mucocutaneous leishmaniasis, mainly with L. b. braziliensis and L. b. panamensis.
To describe the clinical findings of Israeli travelers infected with cutaneous South American leishmaniasis and to draw attention to this problem.
Ten patients were interviewed, examined and treated.
Twenty-two lesions of cutaneous leishmaniasis were found, all in exposed areas. Patients were seen by an average three physicians (range 1-6) before the final diagnosis was confirmed by direct smear, after an average period of 125 days (range 88-270 days). Treatment with Pentostam was started after an average period of 134 days (range 94-275 days). All lesions healed completely, but with scarring.
Travelers to endemic areas, as well as physicians, should be instructed about the potential risks and the clinical manifestations of cutaneous and mucocutaneous South American leishmaniasis. Such awareness will prevent undue delay in diagnosis and treatment.
皮肤型南美利什曼病由多种利什曼原虫引起。缺乏适当治疗可能导致黏膜皮肤型利什曼病，主要由巴西利什曼原虫和巴拿马利什曼原虫引起。
描述感染皮肤型南美利什曼病的以色列旅行者的临床症状，并引起对该问题的关注。
对10名患者进行了访谈、检查和治疗。
发现22处皮肤利什曼病病灶，均位于暴露部位。在通过直接涂片确诊最终诊断之前，患者平均看过3名医生（范围为1 - 6名），平均间隔125天（范围为88 - 270天）。平均在134天（范围为94 - 275天）后开始使用喷他脒治疗。所有病灶均完全愈合，但留有瘢痕。
应指导前往流行地区的旅行者以及医生了解皮肤型和黏膜皮肤型南美利什曼病的潜在风险和临床表现。这种意识将防止诊断和治疗的不当延误。
