Boscoboinik D O, Hensey C E, Azzi A
Institut für Biochemie und Molekularbiologie, Universität Bern, Switzerland.
Biochim Biophys Acta. 1990 May 22;1052(3):499-502. doi: 10.1016/0167-4889(90)90161-6.
Evidence is presented suggesting that the Na+/H+ antiporter activity of aortic smooth muscle cells is stimulated by protein kinase C activation. However, once the transporter has been activated, inhibitors of protein kinase C are not effective, supporting a model in which the Na+/H+ antiporter conserves memory of its activation by protein kinase C.
有证据表明，蛋白激酶C的激活可刺激主动脉平滑肌细胞的Na+/H+逆向转运蛋白活性。然而，一旦该转运蛋白被激活，蛋白激酶C抑制剂就不再有效，这支持了一种模型，即Na+/H+逆向转运蛋白保留了其被蛋白激酶C激活的记忆。
