Nagai S
Second Department of Internal Medicine, Kyoto University, Japan.
Nihon Kyobu Shikkan Gakkai Zasshi. 1990 Jan;28(1):86-91.
We evaluated the usefulness of serum ACE, BALF lymphocyte%, CD4+/CD8+ ratio when diagnosing pulmonary parenchymal lesion in patients with sarcoidosis. The results showed the substantial usefulness but lesser specificity. Furthermore, we evaluated the values of the above three parameters in terms of the judgment of the disease activity and the reliability for foreseeing the prognosis in BHL sarcoidosis. Elevated serum ACH had a good relationship with the disease activity in both nonsmoker and smoker cases. BALF lymphocyte % also had in smoker cases. But none of three parameters showed a significant relationship with the prognosis in BHL sarcoidosis.
我们评估了血清血管紧张素转换酶（ACE）、支气管肺泡灌洗液（BALF）淋巴细胞百分比、CD4⁺/CD8⁺比值在结节病患者肺实质病变诊断中的应用价值。结果显示其具有较高的应用价值，但特异性较低。此外，我们还评估了上述三个参数在双侧肺门淋巴结肿大（BHL）型结节病疾病活动度判断及预后预测可靠性方面的价值。血清ACE升高在非吸烟者和吸烟者病例中均与疾病活动度有良好的相关性。BALF淋巴细胞百分比在吸烟者病例中也有相关性。但在BHL型结节病中，这三个参数均与预后无显著相关性。
