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肥厚性瘢痕

Hypertrophic scar.

作者信息

Gabriel Vincent

机构信息

Division of Physical Medicine and Rehabilitation, Fire Fighters Burn Treatment Centre, Foothills Medical Centre, University of Calgary, Calgary, Alberta, Canada.

出版信息

Phys Med Rehabil Clin N Am. 2011 May;22(2):301-10, vi. doi: 10.1016/j.pmr.2011.02.002.

DOI:10.1016/j.pmr.2011.02.002
PMID:21624722
Abstract

Hypertrophic scars are common complications of burn injury and other soft tissue injuries. Excessive extracellular matrix combined with inadequate remodeling of scar tissue results in an aesthetically and functionally unsatisfactory, painful, pruritic scar that can impair function. Treatment options are available to rehabilitation practitioners, but none are entirely satisfactory. An interdisciplinary clinical program is necessary for best outcomes. Challenges to be met by the rehabilitation community include research into the quantification of burn scar measurement, the effects of mechanical forces on wound healing and scar management, and the best combination of surgical, pharmacologic, and therapy interventions to maximize outcome from reconstructive procedures.

摘要

肥厚性瘢痕是烧伤和其他软组织损伤常见的并发症。细胞外基质过多以及瘢痕组织重塑不足会导致瘢痕在美观和功能上都不尽人意,伴有疼痛、瘙痒,还可能影响功能。康复治疗师有多种治疗选择,但都不尽如人意。为了取得最佳效果,需要一个跨学科的临床项目。康复领域需要应对的挑战包括烧伤瘢痕测量量化研究、机械力对伤口愈合和瘢痕管理的影响,以及手术、药物和治疗干预的最佳组合,以最大限度地提高重建手术的效果。

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