光动力灭活治疗单纯疱疹病毒生殖器感染

Treatment of genital herpes simplex virus infection with photodynamic inactivation.

作者信息

Kaufman R H, Adam E, Mirkovic R R, Melnick J L, Young R L

出版信息

Am J Obstet Gynecol. 1978 Dec 15;132(8):861-9. doi: 10.1016/0002-9378(78)90713-5.

Abstract

A double-blind randomized study to evaluate the effect of proflavine in the treatment of genital herpesvirus infection was conducted. One hundred fifty-seven women were studied, of whom 75 were treated with proflavine (treated women) and 82 were treated with placebo (control group). There were 62 women with primary disease and 95 with recurrent infection. Under the conditions by which this study was conducted, there was no apparent difference in the time of healing of lesions, development of recurrences, or virus isolation following treatment in the proflavine-treated and control groups.

摘要

开展了一项双盲随机研究，以评估硫酸普罗黄素治疗生殖器疱疹病毒感染的效果。研究了157名女性，其中75名接受硫酸普罗黄素治疗（治疗组女性），82名接受安慰剂治疗（对照组）。有62名患有原发性疾病的女性和95名患有复发性感染的女性。在本研究进行的条件下，硫酸普罗黄素治疗组和对照组在治疗后病变愈合时间、复发情况或病毒分离方面没有明显差异。