单纯性生殖器疱疹

Tummon I S, Dudley D K, Walters J H

Can Med Assoc J. 1981 Jul 1;125(1):23-9.

Genital herpes is a sexually transmitted disease caused by the herpes simplex virus. Following the initial infection the virus becomes latent in the sacral ganglia. Approximately 80% of patients are then subject to milder but unpredictable recurrences and may shed the virus even when they are asymptomatic. The disorder causes concern because genital herpes in the mother can result in rare but catastrophic neonatal infection and because of a possible association between genital herpes and cancer of the cervix. No effective treatment is as yet available. Weekly monitoring for virus by cervical culture from 32 weeks' gestation is recommended for women with a history of genital herpes and for those whose sexual partner has such a history.

生殖器疱疹是一种由单纯疱疹病毒引起的性传播疾病。初次感染后，病毒潜伏在骶神经节。大约80%的患者随后会经历较轻但不可预测的复发，即使无症状也可能排出病毒。这种疾病令人担忧，因为母亲患生殖器疱疹可能导致罕见但灾难性的新生儿感染，还因为生殖器疱疹与宫颈癌之间可能存在关联。目前尚无有效的治疗方法。建议有生殖器疱疹病史的女性以及性伴侣有此类病史的女性，从妊娠32周起每周通过宫颈培养监测病毒。