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Task shifting for scale-up of HIV care: evaluation of nurse-centered antiretroviral treatment at rural health centers in Rwanda.扩大艾滋病护理规模的任务转移:卢旺达农村卫生中心以护士为中心的抗逆转录病毒治疗评估
PLoS Med. 2009 Oct;6(10):e1000163. doi: 10.1371/journal.pmed.1000163. Epub 2009 Oct 13.
2
Surgical task shifting in Sub-Saharan Africa.撒哈拉以南非洲地区的外科任务转移
PLoS Med. 2009 May 19;6(5):e1000078. doi: 10.1371/journal.pmed.1000078.
3
The number of procedures required to achieve optimal competency with male circumcision: findings from a randomized trial in Rakai, Uganda.实现男性包皮环切术最佳操作能力所需的手术次数:乌干达拉凯一项随机试验的结果
BJU Int. 2009 Aug;104(4):529-32. doi: 10.1111/j.1464-410X.2009.08420.x. Epub 2009 Apr 21.
4
The safety of adult male circumcision in HIV-infected and uninfected men in Rakai, Uganda.乌干达拉凯地区成年男性包皮环切术在感染与未感染艾滋病毒男性中的安全性。
PLoS Med. 2008 Jun 3;5(6):e116. doi: 10.1371/journal.pmed.0050116.
5
Adult male circumcision outcomes: experience in a developing country setting.成年男性包皮环切术的结果:在一个发展中国家环境中的经验。
Urol Int. 2007;78(3):235-40. doi: 10.1159/000099344.
6
Male circumcision for HIV prevention in men in Rakai, Uganda: a randomised trial.乌干达拉凯地区男性包皮环切术预防男性感染艾滋病毒的随机试验。
Lancet. 2007 Feb 24;369(9562):657-66. doi: 10.1016/S0140-6736(07)60313-4.
7
Male circumcision for HIV prevention in young men in Kisumu, Kenya: a randomised controlled trial.肯尼亚基苏木年轻男性包皮环切术预防艾滋病病毒感染的随机对照试验。
Lancet. 2007 Feb 24;369(9562):643-56. doi: 10.1016/S0140-6736(07)60312-2.
8
Male circumcision as a preventive measure against HIV and other sexually transmitted diseases.男性包皮环切术作为预防艾滋病毒和其他性传播疾病的一项措施。
Curr Opin Infect Dis. 2007 Feb;20(1):66-72. doi: 10.1097/QCO.0b013e328011ab73.
9
Randomized, controlled intervention trial of male circumcision for reduction of HIV infection risk: the ANRS 1265 Trial.男性包皮环切术降低HIV感染风险的随机对照干预试验:ANRS 1265试验
PLoS Med. 2005 Nov;2(11):e298. doi: 10.1371/journal.pmed.0020298. Epub 2005 Oct 25.

评估乌干达拉凯地区医生和临床医生提供的背侧切开和套袖男性割礼方法的安全性和有效性。

Evaluation of the safety and efficiency of the dorsal slit and sleeve methods of male circumcision provided by physicians and clinical officers in Rakai, Uganda.

机构信息

Rakai Health Sciences Programme, Makerere University Kampala (MUK), School of Public Health, Kampala, Uganda.

出版信息

BJU Int. 2012 Jan;109(1):104-8. doi: 10.1111/j.1464-410X.2011.10259.x. Epub 2011 May 31.

DOI:10.1111/j.1464-410X.2011.10259.x
PMID:21627752
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4326085/
Abstract

OBJECTIVE

To assess the safety and efficiency of the dorsal slit and sleeve male circumcision (MC) procedures performed by physicians and clinical officers (COs).

PATIENTS AND METHODS

We evaluated the time required for the MC procedure (efficiency) and moderate/severe adverse events (AEs) for MC (safety) by trained physicians and COs using the sleeve and dorsal slit MC methods in a service programme. Univariate and multiple regressions with robust variance estimation were used to assess factors associated with operative duration (linear) and AEs (logistic).

RESULTS

Six physicians and eight COs conducted 1934 and 3218 MCs, respectively; there were 2471 dorsal slit and 2681 sleeve MC procedures. The overall mean operative duration was 33 min for newly trained providers, which decreased to ≈20 min after ≈100 MCs. The adjusted mean operative duration for dorsal slit MC was significantly shorter than that for the sleeve MC method (Δ - 2.7 min, P < 0.001). The operative duration was longer for COs than physicians for the sleeve procedure, but not the dorsal slit procedure; however this difference reduced with increasing numbers of MCs completed. The unadjusted AE rates were 0.6% for dorsal slit MC and 1.4% for the sleeve method (P = 0.006) and 1.5% for physicians and 0.68% for COs (P = 0.003); however, there were no significant differences after multivariate adjustment. Use of bipolar cautery significantly reduced operative duration (Δ - 4.0 min, P = 0.008), but was associated with higher AE rates (adjusted odds ratio 2.13, 95% confidence interval 1.26-3.61, P = 0.005).

CONCLUSION

The dorsal slit MC method is faster than sleeve resection, and can be safely performed by non-physicians; however, use of bipolar cautery may be inadvisable in this setting.

摘要

目的

评估医生和临床医生(CO)实施的背侧切开和套袖式男性割礼(MC)的安全性和效率。

患者和方法

我们通过培训医生和 CO 使用套袖和背侧切开 MC 方法在服务项目中评估 MC 手术时间(效率)和中度/重度不良事件(AE)(安全性)。使用具有稳健方差估计的单变量和多变量回归评估与手术时间(线性)和 AE(逻辑)相关的因素。

结果

6 名医生和 8 名 CO 分别进行了 1934 例和 3218 例 MC,其中 2471 例采用背侧切开法,2681 例采用套袖 MC 法。新培训人员的总体平均手术时间为 33 分钟,在完成约 100 例 MC 后,降至 ≈20 分钟。背侧切开 MC 的调整后平均手术时间明显短于套袖 MC 方法(Δ-2.7 分钟,P<0.001)。对于套袖手术,CO 的手术时间长于医生,但对于背侧切开手术则不是;然而,随着 MC 完成数量的增加,这种差异会减小。背侧切开 MC 的未调整 AE 率为 0.6%,套袖方法为 1.4%(P=0.006),医生为 1.5%,CO 为 0.68%(P=0.003);然而,多变量调整后没有显著差异。使用双极电凝术可显著缩短手术时间(Δ-4.0 分钟,P=0.008),但与更高的 AE 率相关(调整后的优势比为 2.13,95%置信区间为 1.26-3.61,P=0.005)。

结论

背侧切开 MC 方法比套袖切除术更快,非医生也可以安全实施;然而,在这种情况下,使用双极电凝术可能是不可取的。