Division of General Internal Medicine, University of Miami Miller School of Medicine, Miami, Florida, USA.
Clin Gastroenterol Hepatol. 2011 Oct;9(10):834-41; quiz e109-10. doi: 10.1016/j.cgh.2011.04.027. Epub 2011 May 12.
Chronic liver disease is a major cause of morbidity and mortality among Hispanic people living in the United States. Environmental, genetic, and behavioral factors, as well as socioeconomic and health care disparities among this ethnic group have emerged as important public health concerns. We review the epidemiology, natural history, and response to therapy of chronic liver disease in Hispanic patients. The review covers nonalcoholic fatty liver disease, viral hepatitis B and C, coinfection of viral hepatitis with human immunodeficiency virus, alcoholic cirrhosis, hepatocellular carcinoma, autoimmune hepatitis, and primary biliary cirrhosis. For most of these disorders, the Hispanic population has a higher incidence and more aggressive pattern of disease and overall worse treatment outcomes than in the non-Hispanic white population. Clinicians should be aware of these differences in caring for Hispanic patients with chronic liver disease.
慢性肝病是生活在美国的西班牙裔人群发病率和死亡率的主要原因。环境、遗传和行为因素，以及该族裔在社会经济和医疗保健方面的差异，已成为重要的公共卫生关注点。我们综述了西班牙裔患者慢性肝病的流行病学、自然史和治疗反应。综述涵盖了非酒精性脂肪性肝病、乙型和丙型病毒性肝炎、病毒性肝炎与人类免疫缺陷病毒的合并感染、酒精性肝硬化、肝细胞癌、自身免疫性肝炎和原发性胆汁性肝硬化。对于大多数这些疾病，西班牙裔人群的发病率更高，疾病进展更具侵袭性，整体治疗结局比非西班牙裔白人群更差。临床医生在治疗患有慢性肝病的西班牙裔患者时应注意这些差异。
