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免疫功能低下患者的 CLABSI 发生率:有价值的以患者为中心的结局指标?

CLABSI rates in immunocompromised patients: a valuable patient centered outcome?

机构信息

Department of Infectious Disease, Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

Clin Infect Dis. 2011 Jun 15;52(12):1446-50. doi: 10.1093/cid/cir200.

Abstract

The accepted approach to surveillance for hospital-acquired bloodstream infection (HABSI) due to central venous catheters requires use of the National Health and Safety Network (NHSN) definition for catheter-associated bloodstream infection (CLABSI). In this commentary, we discuss our experience with the application of current NHSN surveillance definitions for CLABSI and the impact that public reporting of CLABSI rates in settings with a high prevalence of special populations has on infection prevention (IP) programs. For IP programs to serve the continuous improvement needs of their organizations, surveillance methodologies need to accurately capture the burden of preventable HABSI among immunocompromised individuals with inherent risk for infection. Current NHSN CLABSI definitions lack specificity for complex and heterogeneous patient populations and require modification. Beyond definitions, IP programs must critically assess the value of their current approach to surveillance to assure that patient-centered outcomes are the focus of prevention efforts.

摘要

目前,针对因中心静脉导管引起的医院获得性血流感染(HABSI)的监测方法,需要使用国家卫生安全网络(NHSN)的导管相关性血流感染(CLABSI)定义。在本评论中,我们讨论了我们在应用当前 NHSN 的 CLABSI 监测定义方面的经验,以及在特殊人群高发环境中报告 CLABSI 率对感染预防(IP)计划的影响。为了使 IP 计划满足其组织的持续改进需求,监测方法需要准确捕捉免疫功能低下个体中可预防 HABSI 的负担,这些个体具有感染的固有风险。当前 NHSN 的 CLABSI 定义缺乏对复杂和异质患者群体的特异性,需要进行修改。除了定义之外,IP 计划还必须批判性地评估其当前监测方法的价值,以确保以患者为中心的结果是预防工作的重点。

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