University of Illinois Eye and Ear Infirmary, Department of Ophthalmology and Visual Sciences, Chicago, Illinois 60612, USA.
Ophthalmic Plast Reconstr Surg. 2011 Nov-Dec;27(6):e156-8. doi: 10.1097/IOP.0b013e318208319d.
A full-term female infant with severe unilateral microphthalmos and ipsilateral orbital hemangioma in the setting of PHACE syndrome was successfully managed with oral propranolol therapy and subsequent orbital conformer placement. After 3 months of systemic propranolol therapy, the orbital hemangioma had shown significant regression without systemic or local complications. The authors believe this to be the first reported use of systemic propranolol therapy in the management of a hemangioma within a microphthalmic orbit of a patient with PHACE syndrome.
一例患有 PHACE 综合征的足月女性婴儿，其单侧严重小眼畸形伴同侧眶部血管瘤，成功地接受了口服普萘洛尔治疗和随后的眼眶成形器放置治疗。在系统使用普萘洛尔治疗 3 个月后，眶部血管瘤显著消退，且无全身或局部并发症。作者认为这是首例报告的 PHACE 综合征患者小眼畸形眶内血管瘤应用全身普萘洛尔治疗的案例。
